STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C4R2D9_KOMPGSAGA-associated factor 11; Functions as component of the transcription regulatory histone acetylation (HAT) complex SAGA. At the promoters, SAGA is required for recruitment of the basal transcription machinery. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination. SAGA acetylates nucleosomal histone H3 to some extent (to form H3K9ac, H3K14ac, H3K18ac and H3K23ac). SAGA interacts with DNA [...] (123 aa)    
Predicted Functional Partners:
SUS1
Transcription and mRNA export factor SUS1; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. At the promoters, SAGA is required for recruitment of the basal transcription machinery. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex required for deubiquitination of [...]
    
 0.988
C4QY61_KOMPG
Ubiquitin carboxyl-terminal hydrolase.
    
 0.983
C4QZ39_KOMPG
Subunit of SAGA histone acetyltransferase complex.
    
 0.983
C4QYV4_KOMPG
Transcription-associated protein; Belongs to the PI3/PI4-kinase family.
    
 0.969
C4R3E4_KOMPG
Transcription initiation protein SPT3.
    
 0.966
C4QZ05_KOMPG
Uncharacterized protein.
   
 0.965
C4R150_KOMPG
Subunit (61/68 kDa) of TFIID and SAGA complexes.
    
 0.964
C4R2A4_KOMPG
Transcriptional regulator involved in glucose repression of Gal4p-regulated genes.
    
 0.960
C4QZA3_KOMPG
Transcriptional coactivator HFI1/ADA1.
    
 0.946
C4QZS5_KOMPG
Transcription initiation factor TFIID subunit 9B.
    
 0.941
Your Current Organism:
Komagataella phaffii
NCBI taxonomy Id: 644223
Other names: K. phaffii GS115, Komagataella phaffii GS115
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.