C4R2H4_KOMPG protein (Komagataella phaffii) - STRING interaction network

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Score

C4R2H4_KOMPG

Guanylate kinase, converts GMP to GDP. (186 aa)

Predicted Functional Partners:

C4QVI1_KOMPG

0.982

C4R373_KOMPG

0.982

C4R300_KOMPG

0.977

C4R748_KOMPG

0.963

C4QWN3_KOMPG

0.960

C4QZZ3_KOMPG

0.960

HAM1

0.946

C4R5V8_KOMPG

0.928

C4R1P9_KOMPG

0.919

C4QYU8_KOMPG

0.915

Your Current Organism:

Komagataella phaffii

NCBI taxonomy Id: 644223
Other names: K. phaffii GS115, Komagataella phaffii GS115

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C4QVI1_KOMPG	C4QWN3_KOMPG	C4QVI1	C4QWN3	GMP synthase, an enzyme that catalyzes the second step in the biosynthesis of GMP from IMP.	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	0.487
C4QVI1_KOMPG	C4QYU8_KOMPG	C4QVI1	C4QYU8	GMP synthase, an enzyme that catalyzes the second step in the biosynthesis of GMP from IMP.	3',5'-cyclic-nucleotide phosphodiesterase.	0.908
C4QVI1_KOMPG	C4QZZ3_KOMPG	C4QVI1	C4QZZ3	GMP synthase, an enzyme that catalyzes the second step in the biosynthesis of GMP from IMP.	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	0.487
C4QVI1_KOMPG	C4R2H4_KOMPG	C4QVI1	C4R2H4	GMP synthase, an enzyme that catalyzes the second step in the biosynthesis of GMP from IMP.	Guanylate kinase, converts GMP to GDP.	0.982
C4QVI1_KOMPG	C4R300_KOMPG	C4QVI1	C4R300	GMP synthase, an enzyme that catalyzes the second step in the biosynthesis of GMP from IMP.	Nucleoside diphosphate kinase.	0.607
C4QVI1_KOMPG	C4R373_KOMPG	C4QVI1	C4R373	GMP synthase, an enzyme that catalyzes the second step in the biosynthesis of GMP from IMP.	Adenine phosphoribosyltransferase, catalyzes the formation of AMP.	0.987
C4QVI1_KOMPG	C4R5V8_KOMPG	C4QVI1	C4R5V8	GMP synthase, an enzyme that catalyzes the second step in the biosynthesis of GMP from IMP.	Dimeric hypoxanthine-guanine phosphoribosyltransferase.	0.916
C4QVI1_KOMPG	HAM1	C4QVI1	C4R6H8	GMP synthase, an enzyme that catalyzes the second step in the biosynthesis of GMP from IMP.	Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.	0.957
C4QWN3_KOMPG	C4QVI1_KOMPG	C4QWN3	C4QVI1	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	GMP synthase, an enzyme that catalyzes the second step in the biosynthesis of GMP from IMP.	0.487
C4QWN3_KOMPG	C4QZZ3_KOMPG	C4QWN3	C4QZZ3	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	0.902
C4QWN3_KOMPG	C4R1P9_KOMPG	C4QWN3	C4R1P9	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	Pyruvate kinase; Belongs to the pyruvate kinase family.	0.908
C4QWN3_KOMPG	C4R2H4_KOMPG	C4QWN3	C4R2H4	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	Guanylate kinase, converts GMP to GDP.	0.960
C4QWN3_KOMPG	C4R300_KOMPG	C4QWN3	C4R300	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	Nucleoside diphosphate kinase.	0.974
C4QWN3_KOMPG	C4R748_KOMPG	C4QWN3	C4R748	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	Small subunit of the ribonucleotide-diphosphate reductase (RNR) complex.	0.997
C4QWN3_KOMPG	HAM1	C4QWN3	C4R6H8	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.	0.639
C4QYU8_KOMPG	C4QVI1_KOMPG	C4QYU8	C4QVI1	3',5'-cyclic-nucleotide phosphodiesterase.	GMP synthase, an enzyme that catalyzes the second step in the biosynthesis of GMP from IMP.	0.908
C4QYU8_KOMPG	C4R2H4_KOMPG	C4QYU8	C4R2H4	3',5'-cyclic-nucleotide phosphodiesterase.	Guanylate kinase, converts GMP to GDP.	0.915
C4QYU8_KOMPG	C4R373_KOMPG	C4QYU8	C4R373	3',5'-cyclic-nucleotide phosphodiesterase.	Adenine phosphoribosyltransferase, catalyzes the formation of AMP.	0.903
C4QYU8_KOMPG	C4R5V8_KOMPG	C4QYU8	C4R5V8	3',5'-cyclic-nucleotide phosphodiesterase.	Dimeric hypoxanthine-guanine phosphoribosyltransferase.	0.900
C4QYU8_KOMPG	HAM1	C4QYU8	C4R6H8	3',5'-cyclic-nucleotide phosphodiesterase.	Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.	0.900