STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C4R3K0_KOMPGProfilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. (126 aa)    
Predicted Functional Partners:
ACT1
Actin; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells; Belongs to the actin family.
   
 0.940
C4R2Z1_KOMPG
Adenylyl cyclase-associated protein; Belongs to the CAP family.
   
 0.857
C4QWL1_KOMPG
Actin-related protein of the dynactin complex; Belongs to the actin family.
   
 0.833
C4R116_KOMPG
Essential component of the Arp2/3 complex; Belongs to the actin family.
   
 0.765
C4QX88_KOMPG
Cofilin, promotes actin filament depolarization in a pH-dependent manner; Belongs to the actin-binding proteins ADF family.
   
 0.754
C4QZB6_KOMPG
Uncharacterized protein.
    
 0.751
C4R8H1_KOMPG
Formin, nucleates the formation of linear actin filaments.
    
 0.751
C4R4M1_KOMPG
Essential component of the Arp2/3 complex; Belongs to the actin family.
   
 0.746
C4QXM9_KOMPG
Actin; Belongs to the actin family.
   
 0.730
C4R4X2_KOMPG
annotation not available
    
 0.725
Your Current Organism:
Komagataella phaffii
NCBI taxonomy Id: 644223
Other names: K. phaffii GS115, Komagataella phaffii GS115
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.