STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C4R3V4_KOMPGOuter kinetochore protein required for chromosome stability. (417 aa)    
Predicted Functional Partners:
C4R0I4_KOMPG
Protein involved in minichromosome maintenance.
   
 
 0.912
C4R1J6_KOMPG
Centromere protein that resembles histones, required for proper kinetochore function.
    
 
 0.885
C4QWW8_KOMPG
CENP-C_C domain-containing protein.
   
 
 0.779
C4R0T1_KOMPG
Uncharacterized protein.
    
 
 0.677
C4QXL2_KOMPG
KIX_2 domain-containing protein.
   
 
 0.642
C4R2J7_KOMPG
Histone H3; Belongs to the histone H3 family.
    
 
 0.597
C4R2J6_KOMPG
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
   
   0.574
C4R1F9_KOMPG
Uncharacterized protein.
    
 
 0.464
C4QWJ9_KOMPG
Uncharacterized protein.
    
 
 0.458
C4R817_KOMPG
Fe2OG dioxygenase domain-containing protein.
    
 
 0.458
Your Current Organism:
Komagataella phaffii
NCBI taxonomy Id: 644223
Other names: K. phaffii GS115, Komagataella phaffii GS115
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.