STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C4R687_KOMPG3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate. (307 aa)    
Predicted Functional Partners:
C4QXQ8_KOMPG
Pantothenate synthase, also known as pantoate-beta-alanine ligase.
 
 0.998
C4R7A4_KOMPG
Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
    
 0.965
C4QYI7_KOMPG
Dihydroxyacid dehydratase.
     
 0.954
C4R807_KOMPG
2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
     
 0.942
C4R1F2_KOMPG
Tryptophan synthase.
     
 0.659
C4R547_KOMPG
Tryptophan synthase.
     
 0.659
C4R637_KOMPG
Anthranilate synthase / indole-3-glycerol phosphate synthase.
   
  
 0.657
C4QVL0_KOMPG
NAD-dependent 5,10-methylenetetrahydrafolate dehydrogenase.
  
  
 0.640
C4R1H2_KOMPG
Uncharacterized protein.
    
  0.635
C4QZV1_KOMPG
N-acetyl-gamma-glutamyl-phosphate reductase / acetylglutamate kinase; In the N-terminal section; belongs to the acetylglutamate kinase family.
     
 0.632
Your Current Organism:
Komagataella phaffii
NCBI taxonomy Id: 644223
Other names: K. phaffii GS115, Komagataella phaffii GS115
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