C4R6B2_KOMPG protein (Komagataella phaffii) - STRING interaction network

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C4R6B2_KOMPG

Component of the Paf1p complex. (1044 aa)

Predicted Functional Partners:

C4R1E6_KOMPG

0.999

C4R3K1_KOMPG

0.999

C4R997_KOMPG

0.999

C4QVU8_KOMPG

0.998

C4QYN1_KOMPG

0.998

C4QYY1_KOMPG

0.997

C4QYQ8_KOMPG

0.993

C4R4Y0_KOMPG

0.984

C4R370_KOMPG

0.981

C4R7H2_KOMPG

0.969

Your Current Organism:

Komagataella phaffii

NCBI taxonomy Id: 644223
Other names: K. phaffii GS115, Komagataella phaffii GS115

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C4QVU8_KOMPG	C4QYN1_KOMPG	C4QVU8	C4QYN1	FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...]	Protein involved in exosome mediated 3' to 5' mRNA degradation.	0.673
C4QVU8_KOMPG	C4QYQ8_KOMPG	C4QVU8	C4QYQ8	FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...]	Subunit of the heterodimeric FACT complex (Spt16p-Pob3p).	0.999
C4QVU8_KOMPG	C4QYY1_KOMPG	C4QVU8	C4QYY1	FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...]	Subunit of the RNA polymerase II-associated Paf1 complex.	0.995
C4QVU8_KOMPG	C4R1E6_KOMPG	C4QVU8	C4R1E6	FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...]	Constituent of Paf1 complex with RNA polymerase II, Paf1p, Hpr1p, Ctr9, Leo1, Rtf1 and Ccr4p.	0.998
C4QVU8_KOMPG	C4R370_KOMPG	C4QVU8	C4R370	FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...]	Protein that forms a complex with Spt4p.	0.993
C4QVU8_KOMPG	C4R3K1_KOMPG	C4QVU8	C4R3K1	FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...]	Uncharacterized protein.	0.998
C4QVU8_KOMPG	C4R4Y0_KOMPG	C4QVU8	C4R4Y0	FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...]	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.976
C4QVU8_KOMPG	C4R6B2_KOMPG	C4QVU8	C4R6B2	FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...]	Component of the Paf1p complex.	0.998
C4QVU8_KOMPG	C4R7H2_KOMPG	C4QVU8	C4R7H2	FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...]	Transcription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family.	0.988
C4QVU8_KOMPG	C4R997_KOMPG	C4QVU8	C4R997	FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...]	RNAP II-associated protein.	0.997
C4QYN1_KOMPG	C4QVU8_KOMPG	C4QYN1	C4QVU8	Protein involved in exosome mediated 3' to 5' mRNA degradation.	FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...]	0.673
C4QYN1_KOMPG	C4QYQ8_KOMPG	C4QYN1	C4QYQ8	Protein involved in exosome mediated 3' to 5' mRNA degradation.	Subunit of the heterodimeric FACT complex (Spt16p-Pob3p).	0.667
C4QYN1_KOMPG	C4QYY1_KOMPG	C4QYN1	C4QYY1	Protein involved in exosome mediated 3' to 5' mRNA degradation.	Subunit of the RNA polymerase II-associated Paf1 complex.	0.865
C4QYN1_KOMPG	C4R1E6_KOMPG	C4QYN1	C4R1E6	Protein involved in exosome mediated 3' to 5' mRNA degradation.	Constituent of Paf1 complex with RNA polymerase II, Paf1p, Hpr1p, Ctr9, Leo1, Rtf1 and Ccr4p.	0.999
C4QYN1_KOMPG	C4R370_KOMPG	C4QYN1	C4R370	Protein involved in exosome mediated 3' to 5' mRNA degradation.	Protein that forms a complex with Spt4p.	0.769
C4QYN1_KOMPG	C4R3K1_KOMPG	C4QYN1	C4R3K1	Protein involved in exosome mediated 3' to 5' mRNA degradation.	Uncharacterized protein.	0.847
C4QYN1_KOMPG	C4R4Y0_KOMPG	C4QYN1	C4R4Y0	Protein involved in exosome mediated 3' to 5' mRNA degradation.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.497
C4QYN1_KOMPG	C4R6B2_KOMPG	C4QYN1	C4R6B2	Protein involved in exosome mediated 3' to 5' mRNA degradation.	Component of the Paf1p complex.	0.998
C4QYN1_KOMPG	C4R7H2_KOMPG	C4QYN1	C4R7H2	Protein involved in exosome mediated 3' to 5' mRNA degradation.	Transcription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family.	0.485
C4QYN1_KOMPG	C4R997_KOMPG	C4QYN1	C4R997	Protein involved in exosome mediated 3' to 5' mRNA degradation.	RNAP II-associated protein.	0.997