STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C4R817_KOMPGFe2OG dioxygenase domain-containing protein. (431 aa)    
Predicted Functional Partners:
C4QZI9_KOMPG
JmjC domain-containing histone demethylase which can specifically demethylate H3K36 tri-and dimethy.
    
 0.992
C4R2J6_KOMPG
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
   
 0.875
C4R0M7_KOMPG
Histone H2B; Belongs to the histone H2B family.
   
 0.839
C4R707_KOMPG
Histone H2A; Belongs to the histone H2A family.
   
 0.818
C4R367_KOMPG
Nucleosomal histone H3-Lys79 methylase, associates with transcriptionally active genes.
   
 0.772
C4R217_KOMPG
Histone-lysine N-methyltransferase, H3 lysine-4 specific; Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation.
   
 0.763
C4R3B5_KOMPG
Uncharacterized protein.
   
 0.740
C4QYZ2_KOMPG
COMPASS component SWD1.
    
 0.724
C4R6S0_KOMPG
Nucleosome assembly factor, involved in chromatin assembly and disassembly.
   
 
 0.713
C4QZ89_KOMPG
Uncharacterized protein.
   
 0.688
Your Current Organism:
Komagataella phaffii
NCBI taxonomy Id: 644223
Other names: K. phaffii GS115, Komagataella phaffii GS115
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.