STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ATG26Sterol 3-beta-glucosyltransferase; Probable sterol 3-beta-glucosyltransferase that mediates autophagic degradation of peroxisomes (pexophagy). Also required for cytoplasm to vacuole transport (Cvt) and autophagic degradation of mitochondria (mitophagy) and nuclei (nucleophagy) (By similarity). Belongs to the glycosyltransferase 28 family. (1211 aa)    
Predicted Functional Partners:
C4R0N6_KOMPG
RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II.
 
      0.816
C4R6G8_KOMPG
Vacuolar aspartyl protease (Proteinase A); Belongs to the peptidase A1 family.
 
      0.692
ATG28
Autophagy-related protein 28; Required for the autophagic degradation of peroxisomes called pexophagy, but not essential for general autophagy. Involved in resistance to elevated pH; Belongs to the ATG28 family.
      
 0.669
PEX19
PEX19 peroxisomal biogenesis protein.
      
 0.611
ATG35
Autophagy-related protein 36; Micropexophagy-specific protein required for efficient micropexophagic apparatus (MIPA) formation but not for general autophagy.
      
 0.607
ATG30
Autophagy-related protein 30; Acts as the peroxisome receptor for pexophagy. Required for both micropexophagy and macropexophagy, but not for the cytoplasm to vacuole transport (Cvt) or autophagy pathways. Required for functional micropexophagic apparatus (MIPA) and relocation of ATG11 to the peroxisome-sequestering arms of the vacuole.
      
 0.607
C4R6R3_KOMPG
Vacuolar membrane protein.
      
 0.607
C4R0I7_KOMPG
Sorting nexin.
   
 
 0.599
C4R840_KOMPG
Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family.
   
  
 0.554
C4QX71_KOMPG
DNA damage-binding protein CMR1; DNA-binding protein that binds to both single- and double- stranded DNA. Binds preferentially to UV-damaged DNA. May be involved in DNA-metabolic processes.
 
  
   0.552
Your Current Organism:
Komagataella phaffii
NCBI taxonomy Id: 644223
Other names: K. phaffii GS115, Komagataella phaffii GS115
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.