STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Cooccurrence
Coexpression
Experiments
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[Homology]
Score
hypAHydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. (125 aa)    
Predicted Functional Partners:
ADC70380.1
TIGRFAM: hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein P47K; KEGG: mja:MJ0442 hydrogenase expression/formation protein (HypB).
 
 
 0.995
ADC69677.1
PFAM: cobalamin synthesis protein P47K; KEGG: mja:MJ0120 urease accessory protein (UreG).
  
 
 0.922
ADC69631.1
Contains selenocysteine; TIGRFAM: coenzyme F420 hydrogenase, subunit alpha; PFAM: nickel-dependent hydrogenase large subunit; KEGG: mja:MJ0029 coenzyme F420-reducing hydrogenase, alpha subunit, selenocysteine-containing; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
 
 
 0.904
ADC68907.1
PFAM: nickel-dependent hydrogenase large subunit; KEGG: mvu:Metvu_0716 nickel-dependent hydrogenase large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
  
 
 0.888
ADC69506.1
PFAM: nickel-dependent hydrogenase large subunit; KEGG: mja:MJ1192m methylviologen-reducing hydrogenase, alpha subunit.
  
 
 0.888
ADC70119.1
PFAM: nickel-dependent hydrogenase large subunit; KEGG: mja:MJ0727 coenzyme F420-reducing hydrogenase, alpha subunit.
  
 
 0.884
ADC68967.1
ATPase-like, ParA/MinD; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.
   
 
 0.875
ADC68723.1
PFAM: Protein of unknown function DUF54; KEGG: mfe:Mefer_0467 protein of unknown function DUF54.
  
    0.865
ADC70118.1
KEGG: mja:MJ0728 carbon monoxide dehydrogenase, catalytic subunit (CooS); TIGRFAM: carbon-monoxide dehydrogenase, catalytic subunit; PFAM: Prismane.
      
 0.790
ADC70132.1
TIGRFAM: [NiFe] hydrogenase maturation protein HypF; PFAM: SUA5/yciO/yrdC domain; acylphosphatase; zinc finger HypF domain protein; KEGG: mja:MJ0713 hydrogenase expression regulatory protein (HypF).
 
   
 0.785
Your Current Organism:
Methanocaldococcus sp. FS40622
NCBI taxonomy Id: 644281
Other names: M. sp. FS406-22, Methanocaldococcus sp. FS406-22
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