STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
apgMPhosphonopyruvate decarboxylase-related protein; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (411 aa)    
Predicted Functional Partners:
pgk
PFAM: phosphoglycerate kinase; KEGG: mja:MJ0641 phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family.
 
  
 0.935
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
    
 0.925
ADC68913.1
Phosphonopyruvate decarboxylase-related protein; KEGG: mja:MJ0010 BcpC phosphonopyruvate decarboxylase; TIGRFAM: phosphonopyruvate decarboxylase-related protein; PFAM: 2,3-bisphosphoglycerate-independent phosphoglycerate mutase; metalloenzyme domain protein.
  
  
0.915
ADC70302.1
KEGG: mja:MJ1018 D-3-phosphoglycerate dehydrogenase; TIGRFAM: D-3-phosphoglycerate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; amino acid-binding ACT domain protein.
    
 0.913
ADC69499.1
PFAM: Aldehyde ferredoxin oxidoreductase; aldehyde ferredoxin oxidoreductase; SMART: Aldehyde ferredoxin oxidoreductase; KEGG: mja:MJ1185 putative aldehyde ferredoxin oxidoreductase (aor).
    
  0.904
pgi
PFAM: phosphoglucose isomerase (PGI); KEGG: mja:MJ1605 glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 
 0.892
ADC68851.1
Alpha-amylase; PFAM: glycoside hydrolase family 57; KEGG: mja:MJ1611 alpha-amylase (AmyA).
       0.871
fbp
Protein of unknown function DUF100; Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P).
 
  
 0.862
aroA
Predicted phospho-2-dehydro-3-deoxyheptonate aldolase; Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7- dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids.
     
 0.833
ADC68891.1
PFAM: deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; KEGG: mja:MJ1585 aldolase.
     
 0.827
Your Current Organism:
Methanocaldococcus sp. FS40622
NCBI taxonomy Id: 644281
Other names: M. sp. FS406-22, Methanocaldococcus sp. FS406-22
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