STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADC68873.1PFAM: transcriptional regulator TrmB; KEGG: mja:MJ1082 hypothetical protein. (124 aa)    
Predicted Functional Partners:
ADC68874.1
PFAM: protein of unknown function UPF0047; KEGG: mja:MJ1081 hypothetical protein.
       0.719
ADC68872.1
PFAM: NADPH-dependent FMN reductase; KEGG: mja:MJ1083 iron-sulfur flavoprotein (isf).
       0.631
ADC70306.1
PFAM: PUA domain containing protein; SMART: PUA domain containing protein; KEGG: mja:MJ1022 queuine tRNA-ribosyltransferase.
 
     0.602
ADC69410.1
PFAM: Protein of unknown function DUF54; KEGG: mja:MJ1564 hypothetical protein; Belongs to the UPF0201 family.
  
     0.557
ef1b
Translation elongation factor aEF-1 beta; Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA.
  
     0.519
ADC69640.1
PFAM: Radical SAM domain protein; KEGG: mja:MJ0021 hypothetical protein.
  
     0.517
ADC68723.1
PFAM: Protein of unknown function DUF54; KEGG: mfe:Mefer_0467 protein of unknown function DUF54.
  
     0.478
aroE
Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
       0.478
ADC69154.1
PFAM: amino acid-binding ACT domain protein; KEGG: mja:MJ1601 hypothetical protein.
  
     0.477
ADC69130.1
PFAM: Protein of unknown function DUF555; KEGG: mfe:Mefer_0415 protein of unknown function DUF555; Belongs to the UPF0212 family.
  
     0.470
Your Current Organism:
Methanocaldococcus sp. FS40622
NCBI taxonomy Id: 644281
Other names: M. sp. FS406-22, Methanocaldococcus sp. FS406-22
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.