STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nadENAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. (253 aa)    
Predicted Functional Partners:
nadK
ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
 
  
 0.977
ADC69007.1
KEGG: mja:MJ0541 nicotinamide-nucleotide adenylyltransferase; TIGRFAM: nicotinamide-nucleotide adenylyltransferase; cytidyltransferase-related domain protein; PFAM: cytidylyltransferase.
 
  
 0.949
nadA
Quinolinate synthetase complex, A subunit; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
  
  
 0.915
ADC70435.1
Nicotinate-nucleotide pyrophosphorylase; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family.
     
 0.907
ADC68749.1
TIGRFAM: asparagine synthase (glutamine-hydrolyzing); PFAM: asparagine synthase; glutamine amidotransferase class-II; KEGG: mja:MJ1116 asparagine synthetase (AsnB).
     
 0.751
ADC70185.1
PFAM: protein of unknown function DUF752; KEGG: mja:MJ0670 hypothetical protein.
 
  
 0.664
ADC70432.1
PFAM: Lactate/malate dehydrogenase; KEGG: mja:MJ0490 malate dehydrogenase; Belongs to the LDH/MDH superfamily.
  
 
 0.557
ADC68843.1
biotin/acetyl-CoA-carboxylase ligase; KEGG: mja:MJ1619 biotin operon repressor/biotin--[acetyl-CoA-carboxylase] ligase (BirA); TIGRFAM: biotin/acetyl-CoA-carboxylase ligase; PFAM: biotin/lipoate A/B protein ligase; biotin protein ligase domain protein.
  
  
 0.505
ADC68928.1
PFAM: ferredoxin-dependent glutamate synthase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: mja:MJ1351 glutamate synthase (GltB); Belongs to the glutamate synthase family.
     
 0.501
ADC68923.1
KEGG: mja:MJ1346 glutamine synthetase (GlnA); TIGRFAM: glutamine synthetase, type I; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp.
  
  
 0.496
Your Current Organism:
Methanocaldococcus sp. FS40622
NCBI taxonomy Id: 644281
Other names: M. sp. FS406-22, Methanocaldococcus sp. FS406-22
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