STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
amzAPeptidase zinc-dependent; Probable zinc metalloprotease whose natural substrate is unknown. (177 aa)    
Predicted Functional Partners:
ADC68964.1
KEGG: hypothetical protein.
       0.642
ADC68965.1
PFAM: DNA polymerase beta domain protein region; KEGG: conserved hypothetical protein; K02331 DNA polymerase phi subunit.
       0.609
nth
DNA-(apurinic or apyrimidinic site) lyase; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
 
     0.516
ADC68966.1
PFAM: pyridoxamine 5'-phosphate oxidase-related FMN-binding; KEGG: mja:MJ0282 hypothetical protein.
       0.457
ADC70162.1
PFAM: DNA-binding TFAR19-related protein; KEGG: mja:MJ0691 hypothetical protein; Belongs to the PDCD5 family.
  
    0.413
Your Current Organism:
Methanocaldococcus sp. FS40622
NCBI taxonomy Id: 644281
Other names: M. sp. FS406-22, Methanocaldococcus sp. FS406-22
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