STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADC68996.1PFAM: formylmethanofuran dehydrogenase subunit E region; KEGG: mvu:Metvu_0708 formylmethanofuran dehydrogenase subunit E region. (216 aa)    
Predicted Functional Partners:
ADC69404.1
PFAM: cobalamin (vitamin B12) biosynthesis CbiM protein; KEGG: mja:MJ1569 cobalt transport protein CbiM.
  
    0.949
ftr
Formylmethanofuran/tetrahydromethanopterin N-formyltransferase; Catalyzes the reversible transfer of a formyl group from formylmethanofuran (formyl-MFR) to tetrahydromethanopterin (H(4)MPT) so as to produce 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) and methanofuran (MFR); Belongs to the FTR family.
     
 0.916
ADC69403.1
KEGG: mja:MJ1570 hypothetical protein.
  
    0.778
ADC68903.1
PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; KEGG: mja:MJ0006 formate dehydrogenase, alpha subunit.
  
 
 0.766
ADC68932.1
Contains selenocysteine; TIGRFAM: formate dehydrogenase, alpha subunit; PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide-binding region; KEGG: mfe:Mefer_0653 formate dehydrogenase, alpha subunit.
  
 
 0.766
ADC70118.1
KEGG: mja:MJ0728 carbon monoxide dehydrogenase, catalytic subunit (CooS); TIGRFAM: carbon-monoxide dehydrogenase, catalytic subunit; PFAM: Prismane.
  
  
  0.734
ADC68902.1
PFAM: coenzyme F420 hydrogenase/dehydrogenase beta subunit domain protein; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: mja:MJ0005 formate dehydrogenase, beta subunit.
  
 
 0.708
ADC68931.1
PFAM: coenzyme F420 hydrogenase/dehydrogenase beta subunit domain protein; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: mja:MJ0005 formate dehydrogenase, beta subunit.
  
 
 0.708
cdhA
CO dehydrogenase/acetyl-CoA synthase complex, epsilon subunit; Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase.
     
 0.700
ADC68819.1
TIGRFAM: CO dehydrogenase/acetyl-CoA synthase complex, epsilon subunit; PFAM: CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit; KEGG: mja:MJ0154 acetyl-CoA decarbonylase/synthase complex subunit epsilon.
     
  0.650
Your Current Organism:
Methanocaldococcus sp. FS40622
NCBI taxonomy Id: 644281
Other names: M. sp. FS406-22, Methanocaldococcus sp. FS406-22
Server load: medium (46%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.