STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lysSKEGG: mfe:Mefer_0785 lysyl-tRNA synthetase; TIGRFAM: lysyl-tRNA synthetase; PFAM: Lysyl-tRNA synthetase, class Ic; Belongs to the class-I aminoacyl-tRNA synthetase family. (530 aa)    
Predicted Functional Partners:
ADC69004.1
KEGG: mja:MJ0538 hypothetical protein.
       0.668
ADC69003.1
PFAM: thiamine pyrophosphate protein domain protein TPP-binding; KEGG: mja:MJ0537 2-oxoglutarate ferredoxin oxidoreductase subunit beta.
       0.608
spt5
NusG antitermination factor; Stimulates transcription elongation; Belongs to the archaeal Spt5 family.
  
    0.594
ADC69002.1
TIGRFAM: pyruvate/ketoisovalerate oxidoreductase, gamma subunit; PFAM: Pyruvate/ketoisovalerate oxidoreductase; KEGG: mja:MJ0536 2-oxoglutarate ferredoxin oxidoreductase subunit gamma.
       0.571
leuS
TIGRFAM: leucyl-tRNA synthetase; KEGG: mja:MJ0633 leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
   
 
 0.467
ADC69006.1
PFAM: Protein of unknown function DUF2097; KEGG: mja:MJ0540 hypothetical protein.
       0.448
rpl18e
PFAM: ribosomal protein L15; KEGG: mja:MJ0193 50S ribosomal protein L18e; Belongs to the eukaryotic ribosomal protein eL18 family.
  
    0.437
ADC69007.1
KEGG: mja:MJ0541 nicotinamide-nucleotide adenylyltransferase; TIGRFAM: nicotinamide-nucleotide adenylyltransferase; cytidyltransferase-related domain protein; PFAM: cytidylyltransferase.
       0.423
ADC69001.1
PFAM: histone deacetylase superfamily; KEGG: mja:MJ0535 acetylpolyamine aminohydrolase (AphA).
       0.421
tyrS
tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 3 subfamily.
   
  
 0.413
Your Current Organism:
Methanocaldococcus sp. FS40622
NCBI taxonomy Id: 644281
Other names: M. sp. FS406-22, Methanocaldococcus sp. FS406-22
Server load: medium (68%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.