STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADC69189.1PFAM: Radical SAM domain protein; cobalamin B12-binding domain protein; surface antigen variable number repeat protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: mfe:Mefer_1154 radical SAM domain protein. (426 aa)    
Predicted Functional Partners:
ADC69190.1
KEGG: mja:MJ1488 hypothetical protein.
  
  
 0.848
ADC70106.1
PFAM: 4-vinyl reductase 4VR; KEGG: mvu:Metvu_0444 4-vinyl reductase 4VR.
 
  
 0.651
ADC70129.1
PFAM: 4-vinyl reductase 4VR; KEGG: mja:MJ0716m hypothetical protein.
 
  
 0.641
ADC68823.1
PFAM: 4-vinyl reductase 4VR; KEGG: mja:MJ0150 hypothetical protein.
  
  
 0.588
ADC69571.1
PFAM: 4-vinyl reductase 4VR; KEGG: mja:MJ1460 hypothetical protein.
  
  
 0.588
ADC69983.1
PFAM: 4-vinyl reductase 4VR; KEGG: mja:MJ0855 hypothetical protein.
  
  
 0.588
purT
Phosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family.
       0.544
ADC69929.1
PFAM: Radical SAM domain protein; KEGG: mja:MJ0907 chondro-6-sulfatase regulatory protein isolog.
 
  
 0.438
ADC69191.1
TIGRFAM: transposase, IS605 OrfB family; PFAM: transposase IS605 OrfB; KEGG: saf:SULAZ_1161 putative transposase DNA-binding domain family.
       0.432
ADC69121.1
Transcriptional regulator NikR, CopG family; PFAM: CopG domain protein DNA-binding domain protein; NikR nickel binding; KEGG: mja:MJ0080 hypothetical protein.
 
    0.427
Your Current Organism:
Methanocaldococcus sp. FS40622
NCBI taxonomy Id: 644281
Other names: M. sp. FS406-22, Methanocaldococcus sp. FS406-22
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.