STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADC69334.1KEGG: mja:MJ1629 hypothetical protein; Belongs to the UPF0282 family. (292 aa)    
Predicted Functional Partners:
ADC69335.1
PFAM: ABC transporter, ATPase, predicted; KEGG: mja:MJ1628 hypothetical protein.
 
     0.658
polC
DNA polymerase II, large subunit DP2; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase.
       0.636
nep1
Suppressor Mra1 family protein; Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA.
 
     0.593
ADC68715.1
PFAM: Protein of unknown function DUF371; KEGG: mja:MJ0206 hypothetical protein.
  
   
 0.532
ADC70361.1
PFAM: THUMP domain protein; KEGG: mja:MJ0421 hypothetical protein.
  
     0.462
rpl18a
PFAM: Ribosomal LX protein; KEGG: mfe:Mefer_1382 ribosomal LX protein.
  
   
 0.422
rgy
Reverse gyrase; Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication; In the C-terminal section; belongs to the prokaryotic type I/III topoisomerase family.
  
     0.420
ADC69410.1
PFAM: Protein of unknown function DUF54; KEGG: mja:MJ1564 hypothetical protein; Belongs to the UPF0201 family.
  
   
 0.418
ADC69331.1
TIGRFAM: alpha-glucan phosphorylase; KEGG: mja:MJ1631 glycogen phosphorylase (GlgP).
       0.415
ADC68723.1
PFAM: Protein of unknown function DUF54; KEGG: mfe:Mefer_0467 protein of unknown function DUF54.
  
   
 0.414
Your Current Organism:
Methanocaldococcus sp. FS40622
NCBI taxonomy Id: 644281
Other names: M. sp. FS406-22, Methanocaldococcus sp. FS406-22
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