STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADC69352.1PFAM: Extracellular ligand-binding receptor; KEGG: mvu:Metvu_0682 extracellular ligand-binding receptor. (433 aa)    
Predicted Functional Partners:
ADC69349.1
PFAM: inner-membrane translocator; KEGG: mja:MJ1269 high-affinity branched-chain amino acid transport protein (BraD).
 
 
 0.997
ADC69351.1
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: mja:MJ1267 high-affinity branched-chain amino acid transport ATP-binding protein (BraF).
 
 
 0.996
ADC69350.1
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: mvu:Metvu_0680 ABC transporter releated protein.
 
 
 0.994
ADC69353.1
PFAM: Extracellular ligand-binding receptor; KEGG: mja:MJ1266 high-affinity branched-chain amino acid transport protein (BraC).
 
  
 
0.947
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
  
 
 0.445
Your Current Organism:
Methanocaldococcus sp. FS40622
NCBI taxonomy Id: 644281
Other names: M. sp. FS406-22, Methanocaldococcus sp. FS406-22
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