STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADC69498.1KEGG: mfe:Mefer_0231 riboflavin synthase; TIGRFAM: riboflavin synthase; PFAM: 67-dimethyl-8-ribityllumazine synthase. (156 aa)    
Predicted Functional Partners:
ribH
6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family.
 
  
  0.952
ribK
CTP-dependent riboflavin kinase; Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN); Belongs to the archaeal riboflavin kinase family.
    
  0.913
ADC69497.1
PFAM: conserved hypothetical protein; KEGG: mja:MJ1183 hypothetical protein.
 
     0.870
ADC69496.1
KEGG: mja:MJ1182 hypothetical protein.
       0.726
ribB
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
 
   
 0.552
ADC69711.1
PFAM: protein of unknown function DUF167; KEGG: mja:MJ0618 hypothetical protein; Belongs to the UPF0235 family.
 
     0.481
ADC70345.1
PFAM: conserved hypothetical protein; KEGG: mja:MJ0405 hypothetical protein.
  
     0.474
ADC69548.1
PFAM: AIR synthase related protein domain protein; AIR synthase related protein; KEGG: mja:MJ1416 hypothetical protein.
  
     0.468
spt4
DNA-directed RNA polymerase subunit E, RpoE2; Stimulates transcription elongation; Belongs to the archaeal Spt4 family.
  
     0.438
ADC69495.1
KEGG: mfe:Mefer_0146 ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic components.
       0.429
Your Current Organism:
Methanocaldococcus sp. FS40622
NCBI taxonomy Id: 644281
Other names: M. sp. FS406-22, Methanocaldococcus sp. FS406-22
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