STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADC69664.1PFAM: cation transporter; KEGG: mja:MJ1485 trk system potassium uptake protein (TrkG). (479 aa)    
Predicted Functional Partners:
ADC69904.1
PFAM: TrkA-N domain protein; TrkA-C domain protein; KEGG: mvu:Metvu_0408 TrkA-N domain protein.
 
 
 0.992
ADC69663.1
KEGG: mja:MJ1484 hypothetical protein.
       0.777
pgk2
PFAM: ATP-cone domain protein; KEGG: mja:MJ1482 2-phosphoglycerate kinase.
 
     0.721
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
     
 0.635
ADC69344.1
PFAM: sodium/hydrogen exchanger; KEGG: mja:MJ1275 Na(+)/H(+) antiporter (NapA).
  
 
 0.536
nadK
ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
       0.525
ADC69225.1
PFAM: sodium/hydrogen exchanger; KEGG: mja:MJ1521 Na+/H+ antiporter.
   
 
 0.515
ADC69661.1
PFAM: Protein of unknown function DUF2100; KEGG: mja:MJ1481 hypothetical protein.
       0.466
ADC69660.1
PFAM: LOR/SDH bifunctional protein conserved domain protein; KEGG: mja:MJ1480 hypothetical protein.
       0.465
ADC69694.1
TIGRFAM: DNA helicase; SMART: DEAD-like helicase; KEGG: mja:MJ0104 DNA-binding protein.
   
 
 0.453
Your Current Organism:
Methanocaldococcus sp. FS40622
NCBI taxonomy Id: 644281
Other names: M. sp. FS406-22, Methanocaldococcus sp. FS406-22
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