STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADC69678.1PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: mja:MJ0121 sn-glycerol-3-phosphate transport ATP-binding protein (UgpC). (261 aa)    
Predicted Functional Partners:
ADC69677.1
PFAM: cobalamin synthesis protein P47K; KEGG: mja:MJ0120 urease accessory protein (UreG).
 
  
 0.999
ADC69676.1
PFAM: Fe-S cluster domain protein; KEGG: mja:MJ0119 carbon monoxide dehydrogenase gamma subunit (CdhE) isolog.
 
    0.998
ADC69183.1
PFAM: (2R)-phospho-3-sulfolactate synthase ComA; KEGG: mja:MJ0255 hypothetical protein.
  
    0.970
ADC69208.1
PFAM: protein of unknown function DUF214; KEGG: mja:MJ1507 hypothetical protein.
  
 
 0.918
ADC70041.1
PFAM: protein of unknown function DUF214; KEGG: mja:MJ0797 hypothetical protein.
  
 
 0.918
ADC70166.1
PFAM: outer membrane lipoprotein carrier protein LolA; KEGG: mja:MJ0687 hypothetical protein.
   
 
 0.868
ADC70380.1
TIGRFAM: hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein P47K; KEGG: mja:MJ0442 hydrogenase expression/formation protein (HypB).
  
  
 0.798
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
     
 0.609
nadK
ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
     
 0.474
rnhB
Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.
  
  
 0.417
Your Current Organism:
Methanocaldococcus sp. FS40622
NCBI taxonomy Id: 644281
Other names: M. sp. FS406-22, Methanocaldococcus sp. FS406-22
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