STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADC69729.1PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; KEGG: mja:MJ0637 prephenate dehydratase. (272 aa)    
Predicted Functional Partners:
ADC68768.1
PFAM: aminotransferase class I and II; KEGG: mfe:Mefer_0825 aminotransferase class I and II.
 
 
 0.981
ADC70265.1
KEGG: mja:MJ0612 prephenate dehydrogenase.
 
 0.977
ADC69730.1
PFAM: Methyltransferase type 11; KEGG: mja:MJ0638 hypothetical protein.
       0.960
ADC70474.1
TIGRFAM: chorismate mutase; PFAM: Chorismate mutase, type II; KEGG: mja:MJ0246 chorismate mutase.
 
 
 0.959
hisC
TIGRFAM: histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; KEGG: mfe:Mefer_0844 histidinol-phosphate aminotransferase.
  
 
 0.951
ADC70169.1
PFAM: aminotransferase class I and II; KEGG: mja:MJ0684 aspartate aminotransferase (aspB2).
 
  
 0.912
ADC69731.1
KEGG: mja:MJ0639 hypothetical protein.
       0.886
aroB
3-dehydroquinate synthase; Catalyzes the oxidative deamination and cyclization of 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3- dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis; Belongs to the archaeal-type DHQ synthase family.
  
  
 0.746
aroA-2
3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
 
  
 0.706
argB
Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.
  
   
 0.643
Your Current Organism:
Methanocaldococcus sp. FS40622
NCBI taxonomy Id: 644281
Other names: M. sp. FS406-22, Methanocaldococcus sp. FS406-22
Server load: medium (50%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.