STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADC69845.1TIGRFAM: CRISPR-associated regulatory protein, DevR family; CRISPR-associated autoregulator DevR family; KEGG: mfe:Mefer_1442 CRISPR-associated autoregulator, DevR family. (301 aa)    
Predicted Functional Partners:
ADC69847.1
KEGG: mfe:Mefer_1440 CRISPR-associated helicase Cas3; TIGRFAM: CRISPR-associated helicase Cas3; PFAM: helicase domain protein; SMART: DEAD-like helicase; helicase domain protein.
 
 
 0.989
ADC69846.1
TIGRFAM: CRISPR-associated protein Cas5; PFAM: protein of unknown function DUF522; KEGG: mfe:Mefer_1441 CRISPR-associated protein Cas5.
  
 
 0.966
ADC69854.1
KEGG: mfe:Mefer_1433 CRISPR-associated helicase Cas3; TIGRFAM: CRISPR-associated helicase Cas3; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein.
 
 
 0.945
ADC69852.1
TIGRFAM: CRISPR-associated protein Cas5 family; PFAM: CRISPR-associated protein, MJ0382; KEGG: mfe:Mefer_1435 CRISPR-associated protein Cas5 family.
  
 
 0.913
ADC69855.1
TIGRFAM: CRISPR-associated HD domain protein; KEGG: mfe:Mefer_1432 CRISPR-associated HD domain protein.
   
 
 0.897
ADC69848.1
CRISPR-associated protein Cas4; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Belongs to the CRISPR-associated exonuclease Cas4 family.
 
   
 0.893
cas1
CRISPR-associated protein Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
 
   
 0.877
ADC69844.1
KEGG: mfe:Mefer_1443 hypothetical protein.
       0.805
ADC69843.1
TIGRFAM: CRISPR-associated protein Cas6; PFAM: protein of unknown function DUF57; KEGG: mja:MJ0375 hypothetical protein.
 
   
 0.710
ADC69856.1
TIGRFAM: CRISPR locus-related DNA-binding protein; KEGG: mfe:Mefer_1431 transcriptional regulator, ArsR family.
     
 0.526
Your Current Organism:
Methanocaldococcus sp. FS40622
NCBI taxonomy Id: 644281
Other names: M. sp. FS406-22, Methanocaldococcus sp. FS406-22
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.