STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
oggDNA-(apurinic or apyrimidinic site) lyase; Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine = 7-oxoG) from DNA. Also nicks DNA at apurinic/apyrimidinic sites (AP sites); Belongs to the type-2 OGG1 family. (206 aa)    
Predicted Functional Partners:
ADC69307.1
PFAM: HhH-GPD family protein; SMART: HhH-GPD family protein; KEGG: mja:MJ1434 endonuclease III, putative (nth2).
  
   
 0.907
ADC70121.1
PFAM: coenzyme F420 hydrogenase/dehydrogenase beta subunit domain protein; KEGG: mja:MJ0725 coenzyme F420-reducing hydrogenase subunit beta.
       0.710
ndk
Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
      
 0.573
ADC70120.1
PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: mja:MJ0726 coenzyme F420-reducing hydrogenase, gamma subunit.
       0.458
ADC70119.1
PFAM: nickel-dependent hydrogenase large subunit; KEGG: mja:MJ0727 coenzyme F420-reducing hydrogenase, alpha subunit.
       0.446
ADC70085.1
Putative transcriptional regulator, CopG family; PFAM: CopG domain protein DNA-binding domain protein; KEGG: mja:MJ0767 hypothetical protein.
       0.435
infB
Translation initiation factor aIF-2; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2.
       0.426
ADC69366.1
Transcriptional regulator, MarR family; PFAM: regulatory protein MarR; KEGG: mja:MJ1254 hypothetical protein.
  
     0.400
Your Current Organism:
Methanocaldococcus sp. FS40622
NCBI taxonomy Id: 644281
Other names: M. sp. FS406-22, Methanocaldococcus sp. FS406-22
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