STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADC70136.1TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; KEGG: mja:MJ0709 hypothetical protein. (452 aa)    
Predicted Functional Partners:
ADC69964.1
KEGG: mfe:Mefer_1135 daunorubicin resistance ABC transporter ATPase subunit; TIGRFAM: daunorubicin resistance ABC transporter ATPase subunit; PFAM: ABC transporter related; SMART: AAA ATPase.
  
  
 0.952
tbp
TATA-box binding family protein; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.
   
  
 0.884
ADC70135.1
PFAM: putative RNA methylase; THUMP domain protein; KEGG: mja:MJ0710 hypothetical protein.
  
    0.875
gap
Glyceraldehyde-3-phosphate dehydrogenase, type II; KEGG: mja:MJ1146 glyceraldehyde-3-phosphate dehydrogenase; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type II; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain; Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain.
 
  
 0.833
ADC69965.1
TIGRFAM: daunorubicin resistance ABC transporter, inner membrane subunit B; PFAM: ABC-2 type transporter; KEGG: mfe:Mefer_1134 daunorubicin resistance ABC transporter, inner membrane subunit B.
  
  
 0.711
ADC70137.1
KEGG: mja:MJ0956 hypothetical protein.
  
    0.584
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
     
 0.566
nadK
ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
     
 0.563
ADC70371.1
Hypothetical protein; KEGG: mvu:Metvu_1417 transcriptional regulator, MarR family.
 
  
 0.509
ADC70138.1
KEGG: mja:MJ0957 hypothetical protein.
       0.506
Your Current Organism:
Methanocaldococcus sp. FS40622
NCBI taxonomy Id: 644281
Other names: M. sp. FS406-22, Methanocaldococcus sp. FS406-22
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