STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADC70144.1TIGRFAM: 3-hydroxy-3-methylglutaryl Coenzyme A reductase; PFAM: hydroxymethylglutaryl-coenzyme A reductase; KEGG: mja:MJ0705 3-hydroxy-3-methylglutaryl coenzyme A reductase; Belongs to the HMG-CoA reductase family. (404 aa)    
Predicted Functional Partners:
ADC69427.1
TIGRFAM: hydroxymethylglutaryl-CoA synthase; PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III domain protein; Hydroxymethylglutaryl-coenzyme A synthase domain; KEGG: mja:MJ1546 hypothetical protein; Belongs to the thiolase-like superfamily. UPF0219 family.
 
 0.999
mvk
Mevalonate kinase; Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)- mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids; Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
 
 0.992
ADC70143.1
PFAM: protein of unknown function DUF95 transmembrane; KEGG: mja:MJ0706 hypothetical protein.
       0.963
ADC69471.1
KEGG: mja:MJ1156 cell division protein CDC48; TIGRFAM: AAA family ATPase, CDC48 subfamily; PFAM: AAA ATPase central domain protein; AAA ATPase VAT domain protein; cell division protein 48 CDC48 domain 2; Vps4 oligomerisation domain protein; SMART: AAA ATPase.
 
  
 
 0.793
ADC70145.1
KEGG: mja:MJ0704 hypothetical protein.
       0.769
ADC69979.1
PFAM: Polyprenyl synthetase; KEGG: mja:MJ0860 bifunctional short chain isoprenyl diphosphate synthase (IdsA); Belongs to the FPP/GGPP synthase family.
  
 
 0.710
pyrF
Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
     
 0.687
ADC69426.1
PFAM: Beta-ketoacyl synthase; KEGG: mja:MJ1549 acetyl-CoA acetyltransferase.
 
  
 0.611
ADC70103.1
Putative PAS/PAC sensor protein; PFAM: flavodoxin/nitric oxide synthase; SMART: PAS domain containing protein; KEGG: mvu:Metvu_0447 beta-lactamase domain protein.
      
 0.568
pdaD
KEGG: mja:MJ0316 pyruvoyl-dependent arginine decarboxylase; TIGRFAM: arginine decarboxylase, pyruvoyl-dependent; PFAM: Pyruvoyl-dependent arginine decarboxylase; Belongs to the PdaD family.
      
 0.562
Your Current Organism:
Methanocaldococcus sp. FS40622
NCBI taxonomy Id: 644281
Other names: M. sp. FS406-22, Methanocaldococcus sp. FS406-22
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