STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADC70194.1PFAM: protein of unknown function UPF0153; KEGG: mja:MJ0661 hypothetical protein. (171 aa)    
Predicted Functional Partners:
ADC70193.1
PFAM: phosphoesterase PA-phosphatase related; SMART: phosphoesterase PA-phosphatase related; KEGG: mja:MJ0662 hypothetical protein.
  
    0.874
ADC70192.1
PFAM: thiamine pyrophosphate protein TPP binding domain protein; thiamine pyrophosphate protein domain protein TPP-binding; KEGG: mja:MJ0663 acetolactate synthase large subunit (IlvB); Belongs to the TPP enzyme family.
 
     0.628
ADC70195.1
PFAM: deoxyribonuclease/rho motif-related TRAM; KEGG: mja:MJ0660 hypothetical protein.
       0.541
ADC70191.1
PFAM: DNA topoisomerase type IA zn finger domain protein; KEGG: mja:MJ0664 hypothetical protein.
       0.514
ADC68749.1
TIGRFAM: asparagine synthase (glutamine-hydrolyzing); PFAM: asparagine synthase; glutamine amidotransferase class-II; KEGG: mja:MJ1116 asparagine synthetase (AsnB).
  
    0.466
ADC70078.1
Transcriptional regulator, ArsR family; PFAM: regulatory protein ArsR; ATPase; SMART: regulatory protein ArsR; AAA ATPase; KEGG: mja:MJ0774 hypothetical protein.
 
   
 0.452
dacZ
Protein of unknown function DUF147; Diadenylate cyclase that catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP is a second messenger for intracellular signal transduction involved in the control of important regulatory processes such as osmoregulation.
 
     0.443
Your Current Organism:
Methanocaldococcus sp. FS40622
NCBI taxonomy Id: 644281
Other names: M. sp. FS406-22, Methanocaldococcus sp. FS406-22
Server load: medium (48%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.