STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADC70203.1Putative signal transduction protein with CBS domains; PFAM: CBS domain containing protein; SMART: CBS domain containing protein; KEGG: mja:MJ0653 inosine-5'-monophosphate dehydrogenase (GuaB). (194 aa)    
Predicted Functional Partners:
ADC69534.1
Putative signal transduction protein with CBS domains; PFAM: CBS domain containing protein; SMART: CBS domain containing protein; KEGG: mja:MJ1225 hypothetical protein.
 
   
0.953
tmk
KEGG: mja:MJ0293 thymidylate kinase; TIGRFAM: thymidylate kinase; PFAM: thymidylate kinase.
     
 0.903
ADC69728.1
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: mja:MJ0636 dihydrolipoamide dehydrogenase.
  
 
 0.825
ADC69034.1
Putative signal transduction protein with CBS domains; PFAM: CBS domain containing protein; SMART: CBS domain containing protein; KEGG: mja:MJ1404 hypothetical protein.
 
   
0.809
ADC69915.1
TIGRFAM: small GTP-binding protein; PFAM: GTP-binding protein HSR1-related; KEGG: mja:MJ0920 GTP-binding protein homologue (YphC).
  
 0.611
ADC70205.1
KEGG: mja:MJ0292 putative monovalent cation/H+ antiporter subunit G.
       0.493
ADC69614.1
PFAM: RNA-metabolising metallo-beta-lactamase; KEGG: mja:MJ0047 putative mRNA 3'-end processing factor 1.
  
 
 0.486
guaAB
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
  
 
 0.472
ribH
6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family.
  
 
 0.433
prs
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P).
  
  
 0.432
Your Current Organism:
Methanocaldococcus sp. FS40622
NCBI taxonomy Id: 644281
Other names: M. sp. FS406-22, Methanocaldococcus sp. FS406-22
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