STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADC70216.1PFAM: FeoA family protein; KEGG: mja:MJ0567 hypothetical protein. (82 aa)    
Predicted Functional Partners:
ADC70215.1
TIGRFAM: ferrous iron transport protein B; small GTP-binding protein; PFAM: Ferrous iron transport protein B domain protein; GTP-binding protein HSR1-related; nucleoside recognition domain protein; Ferrous iron transport B domain protein; KEGG: mja:MJ0566 ferrous iron transport protein B (FeoB).
 
  
 0.997
ADC70217.1
Iron (metal) dependent repressor, DtxR family; PFAM: iron dependent repressor; SMART: iron dependent repressor; KEGG: mja:MJ0568 iron dependent repressor.
 
  
 0.751
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
 
   
 0.653
ADC70214.1
KEGG: mja:MJ0565 hypothetical protein.
       0.516
ADC69495.1
KEGG: mfe:Mefer_0146 ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic components.
 
  
 0.436
ADC70387.1
TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein; KEGG: mja:MJ0449 hypothetical protein.
 
   
 0.434
nth
DNA-(apurinic or apyrimidinic site) lyase; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
       0.428
ADC69625.1
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: mja:MJ0035 ABC transporter subunit.
 
   
 0.408
Your Current Organism:
Methanocaldococcus sp. FS40622
NCBI taxonomy Id: 644281
Other names: M. sp. FS406-22, Methanocaldococcus sp. FS406-22
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