| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADC69201.1 | ADC70280.1 | MFS40622_0509 | MFS40622_1609 | PFAM: peptidase dimerisation domain protein; peptidase M20; KEGG: mja:MJ1497 acetylornithine deacetylase (ArgE). | PFAM: Mandelate racemase/muconate lactonizing protein; KEGG: fnu:FN1586 O-succinylbenzoate-CoA synthase. | 0.432 |
| ADC69286.1 | ADC70280.1 | MFS40622_0596 | MFS40622_1609 | 5-carboxymethyl-2-hydroxymuconate Delta-isomerase; PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: mja:MJ1656 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (HpcE). | PFAM: Mandelate racemase/muconate lactonizing protein; KEGG: fnu:FN1586 O-succinylbenzoate-CoA synthase. | 0.403 |
| ADC69286.1 | topA | MFS40622_0596 | MFS40622_0600 | 5-carboxymethyl-2-hydroxymuconate Delta-isomerase; PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: mja:MJ1656 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (HpcE). | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.801 |
| ADC70279.1 | ADC70280.1 | MFS40622_1608 | MFS40622_1609 | PFAM: protein of unknown function DUF1611; KEGG: mka:MK0569 hypothetical protein. | PFAM: Mandelate racemase/muconate lactonizing protein; KEGG: fnu:FN1586 O-succinylbenzoate-CoA synthase. | 0.901 |
| ADC70280.1 | ADC69201.1 | MFS40622_1609 | MFS40622_0509 | PFAM: Mandelate racemase/muconate lactonizing protein; KEGG: fnu:FN1586 O-succinylbenzoate-CoA synthase. | PFAM: peptidase dimerisation domain protein; peptidase M20; KEGG: mja:MJ1497 acetylornithine deacetylase (ArgE). | 0.432 |
| ADC70280.1 | ADC69286.1 | MFS40622_1609 | MFS40622_0596 | PFAM: Mandelate racemase/muconate lactonizing protein; KEGG: fnu:FN1586 O-succinylbenzoate-CoA synthase. | 5-carboxymethyl-2-hydroxymuconate Delta-isomerase; PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: mja:MJ1656 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (HpcE). | 0.403 |
| ADC70280.1 | ADC70279.1 | MFS40622_1609 | MFS40622_1608 | PFAM: Mandelate racemase/muconate lactonizing protein; KEGG: fnu:FN1586 O-succinylbenzoate-CoA synthase. | PFAM: protein of unknown function DUF1611; KEGG: mka:MK0569 hypothetical protein. | 0.901 |
| ADC70280.1 | dapA | MFS40622_1609 | MFS40622_1806 | PFAM: Mandelate racemase/muconate lactonizing protein; KEGG: fnu:FN1586 O-succinylbenzoate-CoA synthase. | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.402 |
| ADC70280.1 | topA | MFS40622_1609 | MFS40622_0600 | PFAM: Mandelate racemase/muconate lactonizing protein; KEGG: fnu:FN1586 O-succinylbenzoate-CoA synthase. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.441 |
| dapA | ADC70280.1 | MFS40622_1806 | MFS40622_1609 | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | PFAM: Mandelate racemase/muconate lactonizing protein; KEGG: fnu:FN1586 O-succinylbenzoate-CoA synthase. | 0.402 |
| dapA | topA | MFS40622_1806 | MFS40622_0600 | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.653 |
| topA | ADC69286.1 | MFS40622_0600 | MFS40622_0596 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 5-carboxymethyl-2-hydroxymuconate Delta-isomerase; PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: mja:MJ1656 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (HpcE). | 0.801 |
| topA | ADC70280.1 | MFS40622_0600 | MFS40622_1609 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | PFAM: Mandelate racemase/muconate lactonizing protein; KEGG: fnu:FN1586 O-succinylbenzoate-CoA synthase. | 0.441 |
| topA | dapA | MFS40622_0600 | MFS40622_1806 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.653 |