STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mtdMethylenetetrahydromethanopterin dehydrogenase; Catalyzes the reversible reduction of methenyl-H(4)MPT(+) to methylene-H(4)MPT. (277 aa)    
Predicted Functional Partners:
hmd
Coenzyme F420-dependent N(5),N(10)-methenyltetrahydromethanopterin reductase; Catalyzes the reversible reduction of methenyl-H(4)MPT(+) to methylene-H(4)MPT.
     
 0.984
mch
Methenyltetrahydromethanopterin cyclohydrolase; Catalyzes the reversible interconversion of 5-formyl-H(4)MPT to methenyl-H(4)MPT(+); Belongs to the MCH family.
    
 0.977
mer
5,10-methylenetetrahydromethanopterin reductase; Catalyzes the reversible reduction of methylene-H(4)MPT to methyl-H(4)MPT; Belongs to the mer family.
  
 
 0.972
ADC69628.1
TIGRFAM: coenzyme F420 hydrogenase, subunit beta; PFAM: coenzyme F420 hydrogenase/dehydrogenase beta subunit domain protein; KEGG: mja:MJ0032 coenzyme F420-reducing hydrogenase subunit beta.
  
 
 0.951
ADC68926.1
PFAM: coenzyme F420 hydrogenase/dehydrogenase beta subunit domain protein; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: mja:MJ1349 coenzyme F420-reducing hydrogenase, beta subunit.
  
 
 0.948
ADC70121.1
PFAM: coenzyme F420 hydrogenase/dehydrogenase beta subunit domain protein; KEGG: mja:MJ0725 coenzyme F420-reducing hydrogenase subunit beta.
  
 
 0.948
ADC69631.1
Contains selenocysteine; TIGRFAM: coenzyme F420 hydrogenase, subunit alpha; PFAM: nickel-dependent hydrogenase large subunit; KEGG: mja:MJ0029 coenzyme F420-reducing hydrogenase, alpha subunit, selenocysteine-containing; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
  
  
 0.931
fae-hps
Formaldehyde-activating enzyme (Fae); Catalyzes the condensation of formaldehyde with tetrahydromethanopterin (H(4)MPT) to 5,10- methylenetetrahydromethanopterin; In the N-terminal section; belongs to the formaldehyde- activating enzyme family.
  
  
 0.930
ADC69630.1
TIGRFAM: coenzyme F420-reducing hydrogenase delta subunit; hydrogenase maturation protease; PFAM: peptidase M52 hydrogen uptake protein; KEGG: mja:MJ0030 coenzyme F420-reducing hydrogenase, delta subunit (FrcD).
  
  
 0.919
ADC70119.1
PFAM: nickel-dependent hydrogenase large subunit; KEGG: mja:MJ0727 coenzyme F420-reducing hydrogenase, alpha subunit.
     
 0.919
Your Current Organism:
Methanocaldococcus sp. FS40622
NCBI taxonomy Id: 644281
Other names: M. sp. FS406-22, Methanocaldococcus sp. FS406-22
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