STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADC70371.1Hypothetical protein; KEGG: mvu:Metvu_1417 transcriptional regulator, MarR family. (124 aa)    
Predicted Functional Partners:
ADC70372.1
KEGG: mja:MJ0433 hypothetical protein.
       0.649
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
     
 0.639
ADC70307.1
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: mja:MJ1023 ABC transporter ATP-binding protein.
 
  
 0.559
ADC68749.1
TIGRFAM: asparagine synthase (glutamine-hydrolyzing); PFAM: asparagine synthase; glutamine amidotransferase class-II; KEGG: mja:MJ1116 asparagine synthetase (AsnB).
  
  
 0.554
ADC70370.1
PFAM: Protein of unknown function DUF361; KEGG: mfe:Mefer_1290 hypothetical protein.
       0.537
ADC70136.1
TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; KEGG: mja:MJ0709 hypothetical protein.
 
  
 0.509
ADC70308.1
KEGG: mja:MJ1024 hypothetical protein.
 
     0.508
tgtA
Archaeosine tRNA-ribosyltransferase; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family.
  
    0.504
ADC69306.1
KEGG: mja:MJ1435 hypothetical protein.
  
  
 0.480
ADC68938.1
PFAM: response regulator receiver; SMART: response regulator receiver; KEGG: mfe:Mefer_0647 response regulator receiver protein.
  
  
 0.466
Your Current Organism:
Methanocaldococcus sp. FS40622
NCBI taxonomy Id: 644281
Other names: M. sp. FS406-22, Methanocaldococcus sp. FS406-22
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