STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Deba_0009COGs: COG0506 Proline dehydrogenase; InterPro IPR002872; KEGG: bba:Bd1251 1-pyrroline-5 carboxylate dehydrogenase; PFAM: Proline dehydrogenase; SPTR: B4VMU2 Delta-1-pyrroline-5-carboxylate dehydrogenase, putative; PFAM: Proline dehydrogenase. (489 aa)    
Predicted Functional Partners:
Deba_1258
COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterProIPR015590:IPR001670:IPR018211:IPR016160:IPR 016162:IPR016161; KEGG: dal:Dalk_3586 aldehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; iron-containing alcohol dehydrogenase; SPTR: B8FGP4 Aldehyde Dehydrogenase; PFAM: Aldehyde dehydrogenase family; Iron-containing alcohol dehydrogenase.
 
 0.971
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
   
 0.936
Deba_0025
Proline-specific peptidase; COGs: COG0596 hydrolase or acyltransferase (alpha/beta hydrolase superfamily); InterPro IPR000073:IPR005945:IPR002410; KEGG: mpl:Mpal_1914 proline-specific peptidase; PFAM: alpha/beta hydrolase fold; SPTR: B8GKS2 Proline-specific peptidase; TIGRFAM: proline-specific peptidase; PFAM: alpha/beta hydrolase fold; TIGRFAM: proline-specific peptidases, Bacillus coagulans-type subfamily; Belongs to the peptidase S33 family.
     
 0.902
Deba_1908
SSS sodium solute transporter superfamily; COGs: COG0591 Na+/proline symporter; InterPro IPR018212:IPR001734:IPR019900; KEGG: dsa:Desal_1510 Na+/solute symporter; PFAM: Na+/solute symporter; SPTR: C6BS96 Na+/solute symporter; TIGRFAM: SSS sodium solute transporter superfamily; PFAM: Sodium:solute symporter family; TIGRFAM: SSS sodium solute transporter superfamily; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
  
  
 0.856
Deba_1491
COGs: COG0372 Citrate synthase; InterProIPR002020:IPR019810:IPR016142:IPR010953:IPR 016141; KEGG: dal:Dalk_4974 citrate synthase I; PFAM: Citrate synthase; PRIAM: Citrate (Si)-synthase; SPTR: B8FDL5 Citrate synthase; TIGRFAM: citrate synthase I; PFAM: Citrate synthase; TIGRFAM: citrate synthase I (hexameric type); Belongs to the citrate synthase family.
   
  
 0.689
Deba_1171
COGs: COG1271 Cytochrome bd-type quinol oxidase subunit 1; InterPro IPR002585; KEGG: sfu:Sfum_0339 cytochrome bd ubiquinol oxidase, subunit I; PFAM: cytochrome bd ubiquinol oxidase subunit I; SPTR: A0LF37 Cytochrome bd ubiquinol oxidase, subunit I; PFAM: Bacterial Cytochrome Ubiquinol Oxidase.
  
 
 0.641
pxpA
LamB/YcsF family protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
   
    0.622
Deba_0479
COGs: COG0077 Prephenate dehydratase; InterProIPR020822:IPR001086:IPR002912:IPR008242:IPR 002701:IPR018528; KEGG: pca:Pcar_1887 chorismate mutase-P and prephenate dehydratase; PFAM: prephenate dehydratase; Chorismate mutase, type II; amino acid-binding ACT domain protein; SPTR: Q1K0T9 Chorismate mutase; PFAM: Prephenate dehydratase; ACT domain; Chorismate mutase type II.
     
 0.568
Deba_0305
COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR000873:IPR020845; KEGG: mhu:Mhun_2392 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: Q2FT08 AMP-dependent synthetase and ligase; PFAM: AMP-binding enzyme.
  
  
 0.467
Deba_0465
acetoacetyl-CoA synthase; COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR000873:IPR005914:IPR020845; KEGG: noc:Noc_2047 acetoacetyl-CoA synthetase; PFAM: AMP-dependent synthetase and ligase; SPTR: Q3J9I9 Acetoacetyl-CoA synthase; TIGRFAM: acetoacetyl-CoA synthase; PFAM: AMP-binding enzyme; TIGRFAM: acetoacetyl-CoA synthase.
  
  
 0.467
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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