Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Deba_0009COGs: COG0506 Proline dehydrogenase; InterPro IPR002872; KEGG: bba:Bd1251 1-pyrroline-5 carboxylate dehydrogenase; PFAM: Proline dehydrogenase; SPTR: B4VMU2 Delta-1-pyrroline-5-carboxylate dehydrogenase, putative; PFAM: Proline dehydrogenase. (489 aa)    
Predicted Functional Partners:
Deba_1258
COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterProIPR015590:IPR001670:IPR018211:IPR016160:IPR 016162:IPR016161; KEGG: dal:Dalk_3586 aldehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; iron-containing alcohol dehydrogenase; SPTR: B8FGP4 Aldehyde Dehydrogenase; PFAM: Aldehyde dehydrogenase family; Iron-containing alcohol dehydrogenase.
 
 0.972
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
   
 0.948
Deba_0025
Proline-specific peptidase; COGs: COG0596 hydrolase or acyltransferase (alpha/beta hydrolase superfamily); InterPro IPR000073:IPR005945:IPR002410; KEGG: mpl:Mpal_1914 proline-specific peptidase; PFAM: alpha/beta hydrolase fold; SPTR: B8GKS2 Proline-specific peptidase; TIGRFAM: proline-specific peptidase; PFAM: alpha/beta hydrolase fold; TIGRFAM: proline-specific peptidases, Bacillus coagulans-type subfamily; Belongs to the peptidase S33 family.
     
 0.906
Deba_1908
SSS sodium solute transporter superfamily; COGs: COG0591 Na+/proline symporter; InterPro IPR018212:IPR001734:IPR019900; KEGG: dsa:Desal_1510 Na+/solute symporter; PFAM: Na+/solute symporter; SPTR: C6BS96 Na+/solute symporter; TIGRFAM: SSS sodium solute transporter superfamily; PFAM: Sodium:solute symporter family; TIGRFAM: SSS sodium solute transporter superfamily; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
  
  
 0.736
Deba_1171
COGs: COG1271 Cytochrome bd-type quinol oxidase subunit 1; InterPro IPR002585; KEGG: sfu:Sfum_0339 cytochrome bd ubiquinol oxidase, subunit I; PFAM: cytochrome bd ubiquinol oxidase subunit I; SPTR: A0LF37 Cytochrome bd ubiquinol oxidase, subunit I; PFAM: Bacterial Cytochrome Ubiquinol Oxidase.
  
 
 0.623
Deba_0479
COGs: COG0077 Prephenate dehydratase; InterProIPR020822:IPR001086:IPR002912:IPR008242:IPR 002701:IPR018528; KEGG: pca:Pcar_1887 chorismate mutase-P and prephenate dehydratase; PFAM: prephenate dehydratase; Chorismate mutase, type II; amino acid-binding ACT domain protein; SPTR: Q1K0T9 Chorismate mutase; PFAM: Prephenate dehydratase; ACT domain; Chorismate mutase type II.
     
 0.488
Deba_0133
COGs: COG0686 Alanine dehydrogenase; InterProIPR007886:IPR007698:IPR016040:IPR008143:IPR 008141; KEGG: dvu:DVU0571 alanine dehydrogenase; PFAM: alanine dehydrogenase/PNT domain protein; PRIAM: Alanine dehydrogenase; SPTR: Q72EK7 Alanine dehydrogenase; TIGRFAM: alanine dehydrogenase; PFAM: Alanine dehydrogenase/PNT, C-terminal domain; Alanine dehydrogenase/PNT, N-terminal domain; TIGRFAM: alanine dehydrogenase; Belongs to the AlaDH/PNT family.
 
  
 0.459
Deba_0010
KEGG: dol:Dole_3245 hypothetical protein; SPTR: A9A0C9 Putative uncharacterized protein; PFAM: YeeE/YedE family (DUF395).
       0.433
Deba_3233
NADH:flavin oxidoreductase/NADH oxidase; COGs: COG1902 NADH:flavin oxidoreductase Old Yellow Enzyme family; InterProIPR001155:IPR013027:IPR000103:IPR013785:IPR 016040; KEGG: dal:Dalk_2520 NADH:flavin oxidoreductase/NADH oxidase; PFAM: NADH:flavin oxidoreductase/NADH oxidase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: B8FFF3 NADH:flavin oxidoreductase/NADH oxidase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; NADH:flavin oxidoreductase / NADH oxidase family.
  
  
 0.432
Deba_0011
SirA family protein; InterPro IPR001455; KEGG: tye:THEYE_A1506 hypothetical protein; PFAM: SirA family protein; SPTR: B5YGA5 Putative uncharacterized protein; PFAM: SirA-like protein; Belongs to the sulfur carrier protein TusA family.
       0.426
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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