Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Deba_0081KEGG: dde:Dde_2148 chemotaxis protein CheZ, putative; SPTR: C8QZ51 Putative chemotaxis phosphatase, CheZ; PFAM: Chemotaxis phosphatase, CheZ. (560 aa)    
Predicted Functional Partners:
Deba_1230
CheW protein; COGs: COG0835 Chemotaxis signal transduction protein; InterPro IPR008207:IPR002545; KEGG: dba:Dbac_0868 CheA signal transduction histidine kinase; PFAM: CheW domain protein; Hpt domain protein; SMART: CheW domain protein; Hpt domain protein; SPTR: C7LPE3 CheA signal transduction histidine kinase; PFAM: CheW-like domain; Hpt domain.
  
 
 0.990
Deba_0677
Response regulator receiver modulated CheW protein; COGs: COG0835 Chemotaxis signal transduction protein; InterPro IPR001789:IPR002545:IPR011006; KEGG: dal:Dalk_0296 response regulator receiver modulated CheW protein; PFAM: CheW domain protein; response regulator receiver; SMART: response regulator receiver; CheW domain protein; SPTR: C8QZE4 Response regulator receiver modulated CheW protein; PFAM: CheW-like domain; Response regulator receiver domain.
  
 
 0.939
Deba_1231
CheA signal transduction histidine kinase; COGs: COG0643 Chemotaxis protein histidine kinase and related kinase; InterProIPR008207:IPR004105:IPR003594:IPR002545:IPR 005467:IPR004358:IPR009082; KEGG: xom:XOO_2693 chemotaxis protein; PFAM: ATP-binding region ATPase domain protein; Signal transducing histidine kinase homodimeric; Hpt domain protein; CheW domain protein; SMART: CheW domain protein; Hpt domain protein; ATP-binding region ATPase domain protein; SPTR: Q2P1X9 Chemotaxis protein; PFAM: CheW-like domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Signal transducing [...]
  
 
 0.928
Deba_2718
Putative CheA signal transduction histidine kinase; COGs: COG0643 Chemotaxis protein histidine kinase and related kinase; InterProIPR003594:IPR002545:IPR009082:IPR004105:IPR 004358:IPR005467; KEGG: rpe:RPE_1193 CheA signal transduction histidine kinases; PFAM: ATP-binding region ATPase domain protein; Signal transducing histidine kinase homodimeric; CheW domain protein; SMART: CheW domain protein; ATP-binding region ATPase domain protein; SPTR: Q07SD9 CheA signal transduction histidine kinases; manually curated; PFAM: CheW-like domain; Histidine kinase-, DNA gyrase B-, and HSP90-like A [...]
  
 
 0.928
Deba_2782
CheA signal transduction histidine kinase; COGs: COG0643 Chemotaxis protein histidine kinase and related kinase; InterProIPR008207:IPR004105:IPR003594:IPR002545:IPR 005467:IPR004358:IPR009082; KEGG: dal:Dalk_0656 CheA signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; Hpt domain protein; Signal transducing histidine kinase homodimeric; CheW domain protein; SMART: CheW domain protein; Hpt domain protein; ATP-binding region ATPase domain protein; SPTR: Q1NT42 CheW-like protein:ATP-binding region, ATPase-like:Signal transducing histidine kinase, homodime [...]
  
 
 0.928
Deba_2322
RNA polymerase, sigma 28 subunit, FliA/WhiG subfamily; COGs: COG1191 DNA-directed RNA polymerase specialized sigma subunit; InterProIPR013325:IPR013324:IPR000943:IPR011991:IPR 007627:IPR007624:IPR007630:IPR014284:IPR012845; KEGG: mgm:Mmc1_3037 FliA/WhiG family RNA polymerase sigma factor; PFAM: sigma-70 region 4 domain protein; sigma-70 region 2 domain protein; sigma-70 region 3 domain protein; SPTR: A0LC35 RNA polymerase, sigma 28 subunit, FliA/WhiG family; TIGRFAM: RNA polymerase sigma factor, FliA/WhiG family; RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; S [...]
  
  
 0.847
Deba_1229
MCP methyltransferase, CheR-type; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.
  
 
 0.768
Deba_2780
MCP methyltransferase, CheR-type; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.
  
 
 0.768
cheB
Response regulator receiver modulated CheB methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
  
  
 0.754
cheB-2
Response regulator receiver modulated CheB methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
  
  
 0.754
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
Server load: low (8%) [HD]