STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Deba_0084GCN5-related N-acetyltransferase; COGs: COG0427 Acetyl-CoA hydrolase; InterPro IPR003702:IPR000182:IPR016181; KEGG: dat:HRM2_05020 putative 4-hydroxybutyrate CoA-transferase; PFAM: GCN5-related N-acetyltransferase; acetyl-CoA hydrolase/transferase; SPTR: C0QHQ8 Putative 4-hydroxybutyrate CoA-transferase; PFAM: Acetyl-CoA hydrolase/transferase N-terminal domain; Acetyltransferase (GNAT) family. (625 aa)    
Predicted Functional Partners:
Deba_0626
Vinylacetyl-CoA Delta-isomerase; COGs: COG2368 Aromatic ring hydroxylase; InterPro IPR006091:IPR013764:IPR004925; KEGG: cbe:Cbei_2100 vinylacetyl-CoA delta-isomerase; PFAM: 4-hydroxyphenylacetate 3-hydroxylase; PRIAM: Vinylacetyl-CoA Delta-isomerase; SPTR: A6LV87 Vinylacetyl-CoA Delta-isomerase; PFAM: 4-hydroxyphenylacetate 3-hydroxylase N terminal; 4-hydroxyphenylacetate 3-hydroxylase C terminal.
 
  
 0.928
Deba_1051
Vinylacetyl-CoA Delta-isomerase; COGs: COG2368 Aromatic ring hydroxylase; InterPro IPR009100:IPR004925:IPR006091:IPR013764; KEGG: chy:CHY_1730 4-hydroxyphenylacetate 3-hydroxylase family protein; PFAM: 4-hydroxyphenylacetate 3-hydroxylase; PRIAM: Vinylacetyl-CoA Delta-isomerase; SPTR: Q3ABD4 4-hydroxyphenylacetate 3-hydroxylase family protein; PFAM: 4-hydroxyphenylacetate 3-hydroxylase N terminal; 4-hydroxyphenylacetate 3-hydroxylase C terminal.
 
  
 0.925
Deba_0155
GCN5-related N-acetyltransferase; COGs: COG0427 Acetyl-CoA hydrolase; InterPro IPR003702:IPR000182:IPR016181; KEGG: sfu:Sfum_0746 acetyl-CoA hydrolase/transferase; PFAM: GCN5-related N-acetyltransferase; acetyl-CoA hydrolase/transferase; SPTR: A0LG92 Acetyl-CoA hydrolase/transferase; PFAM: Acetyl-CoA hydrolase/transferase N-terminal domain; Acetyltransferase (GNAT) family.
 
  
0.923
icmF
methylmalonyl-CoA mutase, large subunit; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
  
  
 0.838
Deba_3134
Short-chain dehydrogenase/reductase SDR; COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterProIPR016040:IPR016083:IPR002539:IPR002198:IPR 003033:IPR002347; KEGG: dal:Dalk_3192 short-chain dehydrogenase/reductase SDR; PFAM: short-chain dehydrogenase/reductase SDR; MaoC domain protein dehydratase; Sterol-binding domain protein; SPTR: B8FGH3 Short-chain dehydrogenase/reductase SDR; PFAM: MaoC like domain; short chain dehydrogenase; SCP-2 sterol transfer family.
  
 
 0.771
Deba_3133
Short-chain dehydrogenase/reductase SDR; COGs: COG3425 3-hydroxy-3-methylglutaryl CoA synthase; InterProIPR016040:IPR016039:IPR016083:IPR013747:IPR 002878:IPR002198:IPR003033:IPR002347; KEGG: dol:Dole_1550 short-chain dehydrogenase/reductase SDR; PFAM: short-chain dehydrogenase/reductase SDR; protein of unknown function DUF35; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III domain protein; Sterol-binding domain protein; SPTR: A8ZZV4 Short-chain dehydrogenase/reductase SDR; PFAM: Rubredoxin-like zinc ribbon domain (DUF35_N); 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C term [...]
  
 
 0.718
Deba_1258
COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterProIPR015590:IPR001670:IPR018211:IPR016160:IPR 016162:IPR016161; KEGG: dal:Dalk_3586 aldehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; iron-containing alcohol dehydrogenase; SPTR: B8FGP4 Aldehyde Dehydrogenase; PFAM: Aldehyde dehydrogenase family; Iron-containing alcohol dehydrogenase.
  
  
 0.698
Deba_2141
Malic protein NAD-binding protein; COGs: COG0281 Malic enzyme; InterProIPR016040:IPR015884:IPR012188:IPR012301:IPR 012302:IPR002505; KEGG: glo:Glov_1262 malic enzyme; PFAM: malic protein NAD-binding; malic protein domain protein; phosphate acetyl/butaryl transferase; SPTR: B3E7A4 Malate dehydrogenase (Oxaloacetate-decarboxylating) (NADP(+))., Phosphate acetyltransferase; PFAM: Malic enzyme, NAD binding domain; Phosphate acetyl/butaryl transferase; Malic enzyme, N-terminal domain; TIGRFAM: phosphate acetyltransferase.
  
 
 0.684
Deba_1380
Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
  
  
 0.659
rnc
Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
   
  
 0.624
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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