STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Cooccurrence
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[Homology]
Score
Deba_0107Putative phage repressor; COGs: COG2932 transcriptional regulator protein; InterProIPR001387:IPR019759:IPR015927:IPR010982:IPR 011056; KEGG: csa:Csal_1365 putative phage repressor; PFAM: helix-turn-helix domain protein; Peptidase S24/S26A/S26B, conserved region; SMART: helix-turn-helix domain protein; SPTR: Q1QXT8 Putative phage repressor; PFAM: Helix-turn-helix; Peptidase S24-like. (252 aa)    
Predicted Functional Partners:
Deba_1950
Transcriptional regulator, XRE family; InterPro IPR001387:IPR013096:IPR011051:IPR014710; KEGG: drt:Dret_1668 transcriptional regulator, XRE family; PFAM: Cupin 2 conserved barrel domain protein; helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; SPTR: C8X3F5 Transcriptional regulator, XRE family; PFAM: Cupin domain; Helix-turn-helix.
  
  
 0.590
Deba_1290
COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789:IPR013767:IPR003018:IPR013656:IPR 003661:IPR003594:IPR008207:IPR005467:IPR000014:IPR000700:I PR004358:IPR001610:IPR011006:IPR009082; KEGG: dvm:DvMF_1096 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS fold domain protein; GAF domain protein; PAS fold-4 domain protein; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS domain con [...]
  
  
 0.523
Deba_1143
Competence/damage-inducible protein CinA; COGs: COG1546 Uncharacterized protein (competence- and mitomycin-induced); InterPro IPR001453:IPR008136:IPR008135; KEGG: gme:Gmet_0196 competence/damage-inducible protein CinA; PFAM: CinA domain protein; molybdopterin binding domain; SPTR: C8QYB6 Competence/damage-inducible protein CinA; TIGRFAM: competence/damage-inducible protein CinA; PFAM: Probable molybdopterin binding domain; Competence-damaged protein; TIGRFAM: competence/damage-inducible protein CinA N-terminal domain; competence/damage-inducible protein CinA C-terminal domain; molybden [...]
     
 0.476
recA
recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
     
 0.451
Deba_2956
MT-A70 family protein; COGs: COG4725 Transcriptional activator adenine-specific DNA methyltransferase; InterPro IPR007757:IPR002052; KEGG: rde:RD1_1079 DNA methyltransferase; PFAM: MT-A70 family protein; SPTR: C8S3H4 MT-A70 family protein; PFAM: MT-A70; Belongs to the MT-A70-like family.
  
    0.444
Deba_2600
Phage/plasmid primase, P4 family; COGs: COG3378 ATPase; InterPro IPR006500:IPR014818:IPR014015; KEGG: dvl:Dvul_0879 hypothetical protein; PFAM: primase P4; SPTR: A1VBT4 Plasmid/phage primase, P4 family; TIGRFAM: phage/plasmid primase, P4 family; PFAM: D5 N terminal like; TIGRFAM: phage/plasmid primase, P4 family, C-terminal domain.
 
  
 0.436
Deba_2561
Phage/plasmid primase, P4 family; COGs: COG3378 ATPase; InterPro IPR006500:IPR014818:IPR014015; KEGG: dvl:Dvul_0879 hypothetical protein; PFAM: primase P4; SPTR: A1VBT4 Plasmid/phage primase, P4 family; TIGRFAM: phage/plasmid primase, P4 family; PFAM: D5 N terminal like; TIGRFAM: phage/plasmid primase, P4 family, C-terminal domain.
 
  
 0.435
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
     
 0.430
Deba_2539
KEGG: cch:Cag_1524 DNA-damage-inducible protein D; SPTR: Q3AQE6 DNA-damage-inducible protein D.
  
  
 0.409
Deba_0105
Integrase catalytic region; InterProIPR001584:IPR012337:IPR009061:IPR009057:IPR 012287; KEGG: dvu:DVU1140 bacteriophage transposase A protein, putative; PFAM: Integrase catalytic region; SPTR: Q72CZ1 Bacteriophage transposase A protein, putative; PFAM: Mu DNA binding, I gamma subdomain; Mu DNA-binding domain; Integrase core domain.
       0.406
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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