Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
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Deba_0146NAD-dependent epimerase/dehydratase; COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR001509:IPR016040; KEGG: rmr:Rmar_1316 NAD-dependent epimerase/dehydratase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: D0MI98 NAD-dependent epimerase/dehydratase; PFAM: NAD dependent epimerase/dehydratase family. (312 aa)    
Predicted Functional Partners:
Deba_2080
Nucleotide sugar dehydrogenase; COGs: COG1004 UDP-glucose 6-dehydrogenase; InterProIPR001732:IPR014026:IPR014027:IPR016040:IPR 008927:IPR013328:IPR017476; KEGG: tye:THEYE_A0998 UDP-glucose 6-dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; PRIAM: UDP-glucose 6-dehydrogenase; SPTR: B5YKR5 UDP-glucose 6-dehydrogenase; TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; UDP-glucose/GDP-mannose dehydrogenase family, central domai [...]
 
 0.947
Deba_0808
Nucleotidyl transferase; COGs: COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon); InterPro IPR011004:IPR005835:IPR018357; KEGG: ank:AnaeK_3750 nucleotidyl transferase; PFAM: Nucleotidyl transferase; SPTR: B4UE03 Nucleotidyl transferase; PFAM: Nucleotidyl transferase.
 
 0.928
Deba_0024
UDP-sulfoquinovose synthase; COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR001509:IPR016040; KEGG: noc:Noc_1509 UDP-sulfoquinovose synthase; PFAM: NAD-dependent epimerase/dehydratase; PRIAM: UDP-sulfoquinovose synthase; SPTR: Q3JB02 UDP-sulfoquinovose synthase; PFAM: NAD dependent epimerase/dehydratase family.
  
  
  0.911
Deba_2290
Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.
  
 
 0.854
Deba_0291
COGs: COG1207 N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains); InterPro IPR001228; KEGG: ppd:Ppro_0501 UDP-N-acetylglucosamine pyrophosphorylase; PFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; SPTR: A1ALB2 Bifunctional protein glmU; PFAM: Nucleotidyl transferase; TIGRFAM: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase.
  
 
 0.825
Deba_2698
Nucleotidyl transferase; COGs: COG0836 Mannose-1-phosphate guanylyltransferase; InterPro IPR005835:IPR001538; KEGG: sat:SYN_01031 mannose-1-phosphate guanylyltransferase; PFAM: Nucleotidyl transferase; mannose-6-phosphate isomerase type II; SPTR: Q2LSE4 Mannose-1-phosphate guanylyltransferase; PFAM: Nucleotidyl transferase; Mannose-6-phosphate isomerase; TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase.
  
 
 0.825
Deba_0147
COGs: COG2515 1-aminocyclopropane-1-carboxylate deaminase; InterPro IPR001926; KEGG: dal:Dalk_2543 1-aminocyclopropane-1-carboxylate deaminase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; PRIAM: 1-aminocyclopropane-1-carboxylate deaminase; SPTR: B8FFH6 1-aminocyclopropane-1-carboxylate deaminase; PFAM: Pyridoxal-phosphate dependent enzyme.
       0.773
rpsS
Ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
   
  0.727
rpsC
Ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.
   
 0.707
rpsQ
30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
   
  0.702
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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