STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
Deba_0155GCN5-related N-acetyltransferase; COGs: COG0427 Acetyl-CoA hydrolase; InterPro IPR003702:IPR000182:IPR016181; KEGG: sfu:Sfum_0746 acetyl-CoA hydrolase/transferase; PFAM: GCN5-related N-acetyltransferase; acetyl-CoA hydrolase/transferase; SPTR: A0LG92 Acetyl-CoA hydrolase/transferase; PFAM: Acetyl-CoA hydrolase/transferase N-terminal domain; Acetyltransferase (GNAT) family. (635 aa)    
Predicted Functional Partners:
icmF
methylmalonyl-CoA mutase, large subunit; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
  
  
 0.835
Deba_3134
Short-chain dehydrogenase/reductase SDR; COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterProIPR016040:IPR016083:IPR002539:IPR002198:IPR 003033:IPR002347; KEGG: dal:Dalk_3192 short-chain dehydrogenase/reductase SDR; PFAM: short-chain dehydrogenase/reductase SDR; MaoC domain protein dehydratase; Sterol-binding domain protein; SPTR: B8FGH3 Short-chain dehydrogenase/reductase SDR; PFAM: MaoC like domain; short chain dehydrogenase; SCP-2 sterol transfer family.
  
 
 0.736
Deba_1258
COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterProIPR015590:IPR001670:IPR018211:IPR016160:IPR 016162:IPR016161; KEGG: dal:Dalk_3586 aldehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; iron-containing alcohol dehydrogenase; SPTR: B8FGP4 Aldehyde Dehydrogenase; PFAM: Aldehyde dehydrogenase family; Iron-containing alcohol dehydrogenase.
  
  
 0.663
Deba_1491
COGs: COG0372 Citrate synthase; InterProIPR002020:IPR019810:IPR016142:IPR010953:IPR 016141; KEGG: dal:Dalk_4974 citrate synthase I; PFAM: Citrate synthase; PRIAM: Citrate (Si)-synthase; SPTR: B8FDL5 Citrate synthase; TIGRFAM: citrate synthase I; PFAM: Citrate synthase; TIGRFAM: citrate synthase I (hexameric type); Belongs to the citrate synthase family.
  
 
 0.634
Deba_2141
Malic protein NAD-binding protein; COGs: COG0281 Malic enzyme; InterProIPR016040:IPR015884:IPR012188:IPR012301:IPR 012302:IPR002505; KEGG: glo:Glov_1262 malic enzyme; PFAM: malic protein NAD-binding; malic protein domain protein; phosphate acetyl/butaryl transferase; SPTR: B3E7A4 Malate dehydrogenase (Oxaloacetate-decarboxylating) (NADP(+))., Phosphate acetyltransferase; PFAM: Malic enzyme, NAD binding domain; Phosphate acetyl/butaryl transferase; Malic enzyme, N-terminal domain; TIGRFAM: phosphate acetyltransferase.
  
 
 0.631
rnc
Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
   
    0.620
Deba_1380
Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
     
 0.615
Deba_3133
Short-chain dehydrogenase/reductase SDR; COGs: COG3425 3-hydroxy-3-methylglutaryl CoA synthase; InterProIPR016040:IPR016039:IPR016083:IPR013747:IPR 002878:IPR002198:IPR003033:IPR002347; KEGG: dol:Dole_1550 short-chain dehydrogenase/reductase SDR; PFAM: short-chain dehydrogenase/reductase SDR; protein of unknown function DUF35; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III domain protein; Sterol-binding domain protein; SPTR: A8ZZV4 Short-chain dehydrogenase/reductase SDR; PFAM: Rubredoxin-like zinc ribbon domain (DUF35_N); 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C term [...]
  
 
 0.598
sucC
succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
   
 
 0.572
Deba_0883
Cobalamin B12-binding domain protein; COGs: COG2185 Methylmalonyl-CoA mutase C-terminal domain/subunit (cobalamin-binding); InterPro IPR006159:IPR006158; KEGG: pth:PTH_1362 methylmalonyl-CoA mutase C-terminal domain-containing protein; PFAM: cobalamin B12-binding domain protein; SPTR: A5D2I7 Methylmalonyl-CoA mutase, C-terminal domain/subunit; PFAM: B12 binding domain; TIGRFAM: methylmalonyl-CoA mutase C-terminal domain.
  
  
 0.526
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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