STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Deba_0167Sua5/YciO/YrdC/YwlC family protein; COGs: COG0009 Putative translation factor (SUA5); InterPro IPR006070:IPR017945:IPR004388; KEGG: ank:AnaeK_1405 SUA5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC domain; SPTR: Q1NKA5 Sua5/YciO/YrdC/YwlC; TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: yrdC domain; TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; Belongs to the SUA5 family. (208 aa)    
Predicted Functional Partners:
purE
Phosphoribosylamine/glycine ligase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR); Belongs to the GARS family.
     
 0.870
prmC
protein-(glutamine-N5) methyltransferase, release factor-specific; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
 
  
 0.809
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
 0.758
tsaD
Metalloendopeptidase, glycoprotease family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.
 
 
 0.708
Deba_0169
Phosphoribosylaminoimidazolecarboxamideformyltra nsferase; COGs: COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful); InterPro IPR011607:IPR013982; KEGG: glo:Glov_2760 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: MGS domain protein; AICARFT/IMPCHase bienzyme formylation region; PRIAM: Phosphoribosylaminoimidazolecarboxamide formyltransferase; SPTR: B3E7F6 Bifunctional purine biosynthesis protein purH; PFAM: AICARFT/IMPCHase bienzyme; MGS-like domain.
       0.699
Deba_2710
Class II aldolase/adducin family protein; COGs: COG0235 Ribulose-5-phosphate 4-epimerase and related epimerase and aldolase; InterPro IPR001303:IPR014710:IPR011051:IPR013096; KEGG: chl:Chy400_0637 class II aldolase/adducin family protein; PFAM: class II aldolase/adducin family protein; Cupin 2 conserved barrel domain protein; SPTR: B9LJP0 Class II aldolase/adducin family protein; PFAM: Cupin domain; Class II Aldolase and Adducin N-terminal domain.
  
    0.635
Deba_0748
Peptidase M22 glycoprotease; COGs: COG1214 Inactive homolog of metal-dependent protease putative molecular chaperone; InterPro IPR000905; KEGG: dps:DP1162 glycoprotein endopeptidase; PFAM: peptidase M22 glycoprotease; SPTR: Q6AP33 Related to glycoprotein endopeptidase; PFAM: Glycoprotease family.
    
 0.605
Deba_0945
Protein of unknown function UPF0079; COGs: COG0802 ATPase or kinase; InterPro IPR003442; KEGG: sat:SYN_02780 ATP/GTP hydrolase; PFAM: protein of unknown function UPF0079; SPTR: Q2LTJ6 ATP/GTP hydrolase; PFAM: Uncharacterised P-loop hydrolase UPF0079; TIGRFAM: conserved hypothetical nucleotide-binding protein.
    
 0.605
Deba_0165
Metal dependent phosphohydrolase; COGs: COG1639 signal transduction protein; InterPro IPR013976:IPR003607:IPR006675; KEGG: dba:Dbac_0476 putative signal transduction protein; PFAM: Metal-dependent hydrolase HDOD; SMART: metal-dependent phosphohydrolase HD region; SPTR: Q1NMB7 Metal-dependent phosphohydrolase, HD subdomain; TIGRFAM: metal dependent phophohydrolase; PFAM: HDOD domain; TIGRFAM: uncharacterized domain HDIG.
       0.600
Deba_0166
KEGG: dsa:Desal_2720 hypothetical protein; SPTR: C6BZD7 Putative uncharacterized protein.
       0.586
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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