STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
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Experiments
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[Homology]
Score
pgl6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (240 aa)    
Predicted Functional Partners:
zwf
Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
 
 0.999
Deba_3180
6-phosphogluconate dehydrogenase, decarboxylating; COGs: COG1023 6-phosphogluconate dehydrogenase; InterProIPR004849:IPR016040:IPR008927:IPR006115:IPR 006114:IPR006183:IPR013328:IPR016059:IPR002204; KEGG: dma:DMR_05560 putative 6-phosphogluconate dehydrogenase; PFAM: 6-phosphogluconate dehydrogenase NAD-binding; 6-phosphogluconate dehydrogenase domain protein; SPTR: C4XI85 Putative 6-phosphogluconate dehydrogenase; TIGRFAM: 6-phosphogluconate dehydrogenase, decarboxylating; PFAM: NAD binding domain of 6-phosphogluconate dehydrogenase; 6-phosphogluconate dehydrogenase, C-terminal domain [...]
 
  
 0.979
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
    
 0.753
Deba_2373
COGs: COG0587 DNA polymerase III alpha subunit; InterProIPR016195:IPR003141:IPR004013:IPR011708:IPR 004365:IPR004805; KEGG: pca:Pcar_1222 DNA polymerase III, alpha subunit; PFAM: DNA polymerase III alpha subunit; PHP domain protein; nucleic acid binding OB-fold tRNA/helicase-type; PRIAM: DNA-directed DNA polymerase; SMART: phosphoesterase PHP domain protein; SPTR: Q3A586 DNA polymerase III, alpha subunit; TIGRFAM: DNA polymerase III, alpha subunit; PFAM: Bacterial DNA polymerase III alpha subunit; PHP domain; OB-fold nucleic acid binding domain; TIGRFAM: DNA-directed DNA polymerase III [...]
  
    0.742
Deba_0381
HPr kinase; KEGG: dma:DMR_18060 hypothetical protein; SPTR: C4XQD2 Putative uncharacterized protein.
  
  
 0.710
Deba_0224
Transketolase; COGs: COG0021 Transketolase; InterProIPR005474:IPR005475:IPR005476:IPR009014:IPR 005478:IPR015941; KEGG: pna:Pnap_4499 transketolase; PFAM: Transketolase domain protein; Transketolase central region; SPTR: A6C7Q1 Transketolase; TIGRFAM: transketolase; PFAM: Transketolase, thiamine diphosphate binding domain; Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain; TIGRFAM: transketolase, bacterial and yeast; Belongs to the transketolase family.
  
 
 0.675
Deba_1290
COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789:IPR013767:IPR003018:IPR013656:IPR 003661:IPR003594:IPR008207:IPR005467:IPR000014:IPR000700:I PR004358:IPR001610:IPR011006:IPR009082; KEGG: dvm:DvMF_1096 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS fold domain protein; GAF domain protein; PAS fold-4 domain protein; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS domain con [...]
  
  
 0.606
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily.
  
 
 0.552
ilvD
COGs: COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase; InterPro IPR000581:IPR004404:IPR020558; KEGG: mja:MJ1276 dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; PRIAM: Dihydroxy-acid dehydratase; SPTR: C5U5V1 Dihydroxy-acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: Dehydratase family; TIGRFAM: dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
  
  
 0.529
Deba_0121
Phosphoglucomutase, alpha-D-glucose phosphate-specific; COGs: COG0033 Phosphoglucomutase; InterProIPR005844:IPR005845:IPR005846:IPR005843:IPR 016055:IPR016066:IPR005852; KEGG: gur:Gura_2654 phosphoglucomutase; PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase; SPTR: A5G4W1 Phosphoglucomutase, alpha-D-glucose phosphate-specific; TIGRFAM: phosphoglucomutase, alpha-D-glucose phosphate-specific; PFAM: [...]
  
 
 0.523
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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