STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
Deba_0254Putative two component, sigma54 specific, transcriptional regulator, Fis family; COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterProIPR001789:IPR002078:IPR011006:IPR009057:IPR 003593; KEGG: dal:Dalk_0736 putative two component, sigma54 specific, transcriptional regulator, Fis family; PFAM: sigma-54 factor interaction domain-containing protein; response regulator receiver; SMART: response regulator receiver; AAA ATPase; SPTR: Q74EW8 Sigma-54 dependent DNA-binding response regulator; PFAM: Response regulator receiver domain; Si [...] (473 aa)    
Predicted Functional Partners:
Deba_1961
RNA polymerase, sigma 54 subunit, RpoN; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
   
 0.727
Deba_1290
COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789:IPR013767:IPR003018:IPR013656:IPR 003661:IPR003594:IPR008207:IPR005467:IPR000014:IPR000700:I PR004358:IPR001610:IPR011006:IPR009082; KEGG: dvm:DvMF_1096 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS fold domain protein; GAF domain protein; PAS fold-4 domain protein; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS domain con [...]
  
 
 0.682
Deba_3291
COGs: COG3852 Signal transduction histidine kinase nitrogen specific; InterProIPR000014:IPR003594:IPR009082:IPR003018:IPR 013656:IPR003661:IPR005467:IPR004358; KEGG: cau:Caur_1383 PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; PAS fold-4 domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; PAS domain containing protein; SPTR: A9W9X5 Sensor protein; TIGRFAM: PAS sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; GAF do [...]
 
 
 0.646
Deba_1230
CheW protein; COGs: COG0835 Chemotaxis signal transduction protein; InterPro IPR008207:IPR002545; KEGG: dba:Dbac_0868 CheA signal transduction histidine kinase; PFAM: CheW domain protein; Hpt domain protein; SMART: CheW domain protein; Hpt domain protein; SPTR: C7LPE3 CheA signal transduction histidine kinase; PFAM: CheW-like domain; Hpt domain.
  
 
 0.607
Deba_0862
COGs: COG3852 Signal transduction histidine kinase nitrogen specific; InterProIPR000014:IPR001610:IPR003661:IPR003594:IPR 001789:IPR005467:IPR000700:IPR011006:IPR009082:IPR004358:I PR013767:IPR000169; KEGG: sfu:Sfum_2401 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; histidine kinase A domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; PAS domain containing protein; PAC repeat-containing protein; histidine kinase A domain protein; response regulator receiver; SPTR: A0LKY0 Sensor p [...]
  
 
 0.598
Deba_1160
COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358:IPR003594:IPR011006:IPR009082:IPR 011620:IPR013655:IPR013656:IPR013767:IPR003661:IPR001789:I PR005467:IPR000014:IPR000700:IPR001610; KEGG: cyn:Cyan7425_3579 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; PAS fold-4 domain protein; PAS fold-3 domain protein; 5TM Receptors of the LytS-YhcK type transmembrane region; histidine kinase A domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; PAS domain containing protein [...]
  
 
 0.598
Deba_1539
COGs: COG3852 Signal transduction histidine kinase nitrogen specific; InterProIPR003661:IPR003594:IPR009082:IPR004358:IPR 005467; KEGG: dba:Dbac_1016 histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: C4T0M4 Sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
 
 
 0.557
Deba_1103
MinD-related ATP-binding protein; COGs: COG0455 ATPase involved in chromosome partitioning; KEGG: bga:BG0748 MinD-related ATP-binding protein; SPTR: C0T1H1 ATP-binding protein; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain.
  
 
 0.523
Deba_2321
Cobyrinic acid ac-diamide synthase; COGs: COG0455 ATPase involved in chromosome partitioning; InterPro IPR002586; KEGG: sfu:Sfum_1383 cobyrinic acid a,c-diamide synthase; PFAM: Cobyrinic acid ac-diamide synthase; SPTR: Q1NP85 Cobyrinic acid a,c-diamide synthase; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain.
  
 
 0.523
Deba_0250
COGs: COG0642 Signal transduction histidine kinase; InterProIPR013656:IPR003018:IPR013767:IPR003661:IPR 003594:IPR001789:IPR005467:IPR000014:IPR000700:IPR011006:I PR009082:IPR004358; KEGG: gur:Gura_2707 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; GAF domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; PAS domain containing protein; response regulator receiver; SPT [...]
  
 
 0.514
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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