STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Deba_0264COGs: COG1763 Molybdopterin-guanine dinucleotide biosynthesis protein; InterPro IPR004435; KEGG: ppd:Ppro_0305 molybdopterin-guanine dinucleotide biosynthesis protein B; PFAM: molybdopterin-guanine dinucleotide biosynthesis MobB region; SPTR: Q1NJ69 Molybdopterin-guanine dinucleotide biosynthesis MobB region; TIGRFAM: molybdopterin-guanine dinucleotide biosynthesis protein B; PFAM: Molybdopterin guanine dinucleotide synthesis protein B; TIGRFAM: molybdopterin-guanine dinucleotide biosynthesis protein MobB. (221 aa)    
Predicted Functional Partners:
mobA
Molybdenum cofactor guanylyltransferase; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family.
 
 
 0.862
Deba_0265
Metal dependent phosphohydrolase; InterPro IPR006674; KEGG: dps:DP1279 hypothetical protein; PFAM: metal-dependent phosphohydrolase HD sub domain; SPTR: Q6ANR6 Putative uncharacterized protein; PFAM: HD domain; TIGRFAM: uncharacterized domain HDIG.
   
   0.809
Deba_0703
Molybdopterin binding domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.
  
 
 0.775
moaC
Molybdenum cofactor biosynthesis protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.
 
  
 0.770
Deba_2841
4Fe-4S ferredoxin iron-sulfur binding domain protein; COGs: COG0437 Fe-S-cluster-containing hydrogenase components 1; InterPro IPR001450:IPR017896:IPR017900; KEGG: sfu:Sfum_3286 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: A0LNF7 4Fe-4S ferredoxin, iron-sulfur binding domain protein.
 
     0.524
Deba_0482
Molybdopterin oxidoreductase; COGs: COG3383 Uncharacterized anaerobic dehydrogenase; InterPro IPR006656:IPR006657:IPR009010; KEGG: sfu:Sfum_0031 molybdopterin oxidoreductase; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; SPTR: A0LE82 Molybdopterin oxidoreductase; PFAM: Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
 
  
 0.512
Deba_2119
Molybdopterin oxidoreductase; COGs: COG3383 Uncharacterized anaerobic dehydrogenase; InterPro IPR009010:IPR006656:IPR006657; KEGG: sfu:Sfum_0031 molybdopterin oxidoreductase; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; SPTR: A0LE82 Molybdopterin oxidoreductase; PFAM: Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
 
  
 0.512
Deba_0261
COGs: COG0778 Nitroreductase; InterPro IPR001450:IPR000415:IPR017896:IPR017900; KEGG: dol:Dole_1688 nitroreductase; PFAM: nitroreductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: A9A0J2 Nitroreductase; PFAM: Nitroreductase family.
   
   0.505
gyrA
DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
     
 0.488
gpsA
NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; COGs: COG0240 Glycerol-3-phosphate dehydrogenase; InterProIPR011128:IPR006109:IPR008927:IPR016040:IPR 006168:IPR013328; KEGG: gem:GM21_0007 glycerol-3-phosphate dehydrogenase (NAD(P)(+)); PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; SPTR: C6E7R1 Glycerol-3-phosphate dehydrogenase [NAD(P)+]; PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
       0.471
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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