Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
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[Homology]
Score
Deba_0265Metal dependent phosphohydrolase; InterPro IPR006674; KEGG: dps:DP1279 hypothetical protein; PFAM: metal-dependent phosphohydrolase HD sub domain; SPTR: Q6ANR6 Putative uncharacterized protein; PFAM: HD domain; TIGRFAM: uncharacterized domain HDIG. (196 aa)    
Predicted Functional Partners:
Deba_0264
COGs: COG1763 Molybdopterin-guanine dinucleotide biosynthesis protein; InterPro IPR004435; KEGG: ppd:Ppro_0305 molybdopterin-guanine dinucleotide biosynthesis protein B; PFAM: molybdopterin-guanine dinucleotide biosynthesis MobB region; SPTR: Q1NJ69 Molybdopterin-guanine dinucleotide biosynthesis MobB region; TIGRFAM: molybdopterin-guanine dinucleotide biosynthesis protein B; PFAM: Molybdopterin guanine dinucleotide synthesis protein B; TIGRFAM: molybdopterin-guanine dinucleotide biosynthesis protein MobB.
   
   0.796
Deba_3067
KEGG: sfu:Sfum_0040 hypothetical protein; SPTR: A0LE91 Putative uncharacterized protein.
 
     0.697
Deba_2047
Conserved hypothetical protein; InterPro IPR016024:IPR011989; KEGG: dal:Dalk_2376 hypothetical protein; SPTR: Q1NTE0 HEAT.
 
    0.651
Deba_1367
Phosphoesterase RecJ domain protein; COGs: COG0618 Exopolyphosphatase-related protein; InterPro IPR001667; KEGG: dol:Dole_0370 phosphoesterase domain-containing protein; PFAM: phosphoesterase RecJ domain protein; SPTR: A8ZT16 Phosphoesterase RecJ domain protein; PFAM: DHH family.
 
   
 0.595
Deba_1999
Protein of unknown function DUF181; COGs: COG1944 conserved hypothetical protein; InterProIPR019734:IPR003776:IPR001440:IPR013105:IPR 013026:IPR011990; KEGG: dol:Dole_1241 hypothetical protein; PFAM: protein of unknown function DUF181; TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SPTR: A8ZY40 Putative uncharacterized protein; PFAM: YcaO-like family; Tetratricopeptide repeat; TIGRFAM: uncharacterized domain; bacteriocin biosynthesis docking scaffold, SagD family.
 
 
   0.560
cysS-2
Cysteine synthase; COGs: COG0215 Cysteinyl-tRNA synthetase; InterProIPR005856:IPR002308:IPR001926:IPR009080:IPR 015803:IPR015273:IPR014729:IPR001216; KEGG: dal:Dalk_3820 cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; Cysteinyl-tRNA synthetase class Ia; Cysteinyl-tRNA synthetase class Ia DALR; SPTR: B8FC88 Cysteine synthase; TIGRFAM: cysteine synthase; cysteinyl-tRNA synthetase; PFAM: tRNA synthetases class I (C) catalytic domain; DALR domain; Pyridoxal-phosphate dependent enzyme; TIGRFAM: glutamate--cysteine ligase/gamma-glutamylcysteine synthetase, Str [...]
 
  
 0.510
Deba_2368
KEGG: tgr:Tgr7_0065 hypothetical protein; SPTR: C0GRH8 Putative uncharacterized protein.
  
     0.509
gyrA
DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
  
  
 0.504
gpsA
NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; COGs: COG0240 Glycerol-3-phosphate dehydrogenase; InterProIPR011128:IPR006109:IPR008927:IPR016040:IPR 006168:IPR013328; KEGG: gem:GM21_0007 glycerol-3-phosphate dehydrogenase (NAD(P)(+)); PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; SPTR: C6E7R1 Glycerol-3-phosphate dehydrogenase [NAD(P)+]; PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
       0.497
Deba_1396
KEGG: dsa:Desal_0956 hypothetical protein; SPTR: C6BZW4 Putative uncharacterized protein.
  
     0.493
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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