Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Deba_0303Cation diffusion facilitator family transporter; COGs: COG0053 Co/Zn/Cd cation transporter; InterPro IPR002524; KEGG: hch:HCH_04023 Co/Zn/Cd cation transporter; PFAM: cation efflux protein; SPTR: Q2SF35 Predicted Co/Zn/Cd cation transporters; TIGRFAM: cation diffusion facilitator family transporter; PFAM: Cation efflux family; TIGRFAM: cation diffusion facilitator family transporter. (309 aa)    
Predicted Functional Partners:
Deba_0304
periplasmic/7TM domain sensor diguanylate cyclase; COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterPro IPR011622:IPR011623:IPR000160:IPR018062; KEGG: dal:Dalk_2685 periplasmic/7TM domain sensor diguanylate cyclase; PFAM: GGDEF domain containing protein; Diverse 7TM receptor transmembrane region; Diverse 7TM receptor extracellular region 2; SMART: GGDEF domain containing protein; SPTR: B8FIY6 Periplasmic/7TM domain sensor diguanylate cyclase; TIGRFAM: diguanylate cyclase; PFAM: 7TM diverse intracellular signalling; GGDEF domain; 7TMR-DISM [...]
       0.770
mdh
Malate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
  
    0.699
Deba_0305
COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR000873:IPR020845; KEGG: mhu:Mhun_2392 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: Q2FT08 AMP-dependent synthetase and ligase; PFAM: AMP-binding enzyme.
 
     0.524
Deba_2329
COGs: COG4786 Flagellar basal body rod protein; InterProIPR019776:IPR001444:IPR010930:IPR020013:IPR 012836; KEGG: geo:Geob_0627 flagellar basal-body rod protein FlgF; PFAM: flagellar basal body rod protein; protein of unknown function DUF1078 domain protein; SPTR: B9M0F5 Flagellar basal-body rod protein FlgF; TIGRFAM: flagellar basal-body rod protein FlgF; fagellar hook-basal body protein; PFAM: Domain of unknown function (DUF1078); Flagella basal body rod protein; TIGRFAM: flagellar basal-body rod protein FlgF; fagellar hook-basal body proteins.
    
 
 0.481
Deba_1238
Protein of unknown function DUF399; COGs: COG3016 Uncharacterized iron-regulated protein; InterPro IPR007314:IPR001478; KEGG: sfu:Sfum_2732 hypothetical protein; PFAM: protein of unknown function DUF399; SMART: PDZ/DHR/GLGF domain protein; SPTR: A0LLV8 Putative uncharacterized protein; PFAM: Protein of unknown function, DUF399; PDZ domain (Also known as DHR or GLGF).
    
 0.466
cmk
COGs: COG0283 Cytidylate kinase; InterPro IPR003136:IPR011994; KEGG: gbm:Gbem_3257 cytidylate kinase; PFAM: cytidylate kinase region; SPTR: C8R0Z9 Cytidylate kinase; TIGRFAM: cytidylate kinase; PFAM: Cytidylate kinase; TIGRFAM: cytidylate kinase.
  
    0.432
Deba_1152
COGs: COG0069 Glutamate synthase domain 2; InterProIPR002489:IPR000583:IPR006982:IPR002932:IPR 013785:IPR017932; KEGG: ttr:Tter_0474 glutamate synthase (ferredoxin); PFAM: ferredoxin-dependent glutamate synthase; glutamine amidotransferase class-II; glutamate synthase; glutamate synthase alpha subunit domain protein; PRIAM: Glutamate synthase (ferredoxin); SPTR: D1CEN9 Glutamate synthase (Ferredoxin); PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II.
     
 0.420
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.