STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
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[Homology]
Score
Deba_0327Two component, sigma54 specific, transcriptional regulator, Fis family; COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterProIPR001789:IPR002078:IPR002197:IPR011006:IPR 009057:IPR003593:IPR020441; KEGG: sat:SYN_02713 response regulator; PFAM: sigma-54 factor interaction domain-containing protein; response regulator receiver; helix-turn-helix Fis-type; SMART: response regulator receiver; AAA ATPase; SPTR: Q2LRW3 Response regulator containing sigma 54 interaction domain; PFAM: Response regulator receiver domain; Bacterial regulat [...] (456 aa)    
Predicted Functional Partners:
Deba_0326
COGs: COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation; InterProIPR003660:IPR013656:IPR003661:IPR003594:IPR 017232:IPR009082:IPR000014:IPR004358:IPR005467; KEGG: gsu:GSU0812 nitrogen regulation protein NtrY, putative; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; PAS domain containing protein; histidine kinase A domain protein; SPTR: Q [...]
 
 0.985
Deba_0328
KEGG: hypothetical protein; SPTR: A2QST1 Putative uncharacterized protein.
       0.773
Deba_1961
RNA polymerase, sigma 54 subunit, RpoN; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
   
 0.704
Deba_1290
COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789:IPR013767:IPR003018:IPR013656:IPR 003661:IPR003594:IPR008207:IPR005467:IPR000014:IPR000700:I PR004358:IPR001610:IPR011006:IPR009082; KEGG: dvm:DvMF_1096 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS fold domain protein; GAF domain protein; PAS fold-4 domain protein; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS domain con [...]
  
 
 0.644
Deba_3291
COGs: COG3852 Signal transduction histidine kinase nitrogen specific; InterProIPR000014:IPR003594:IPR009082:IPR003018:IPR 013656:IPR003661:IPR005467:IPR004358; KEGG: cau:Caur_1383 PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; PAS fold-4 domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; PAS domain containing protein; SPTR: A9W9X5 Sensor protein; TIGRFAM: PAS sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; GAF do [...]
 
 
 0.572
Deba_1539
COGs: COG3852 Signal transduction histidine kinase nitrogen specific; InterProIPR003661:IPR003594:IPR009082:IPR004358:IPR 005467; KEGG: dba:Dbac_1016 histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: C4T0M4 Sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
 
 
 0.537
Deba_0325
Thioesterase superfamily protein; COGs: COG2050 Uncharacterized protein possibly involved in aromatic compounds catabolism; InterPro IPR006683:IPR003736; KEGG: dal:Dalk_2350 thioesterase superfamily protein; PFAM: thioesterase superfamily protein; SPTR: B8FAV7 Thioesterase superfamily protein; PFAM: Thioesterase superfamily; TIGRFAM: uncharacterized domain 1.
       0.512
Deba_1230
CheW protein; COGs: COG0835 Chemotaxis signal transduction protein; InterPro IPR008207:IPR002545; KEGG: dba:Dbac_0868 CheA signal transduction histidine kinase; PFAM: CheW domain protein; Hpt domain protein; SMART: CheW domain protein; Hpt domain protein; SPTR: C7LPE3 CheA signal transduction histidine kinase; PFAM: CheW-like domain; Hpt domain.
  
 
 0.511
Deba_2312
COGs: COG1868 Flagellar motor switch protein; InterPro IPR001543:IPR001689; KEGG: dma:DMR_22580 flagellar motor switch protein FliM; PFAM: flagellar motor switch protein FliM; surface presentation of antigens (SPOA) protein; SPTR: C4XSQ7 Flagellar motor switch protein FliM; TIGRFAM: flagellar motor switch protein FliM; PFAM: Surface presentation of antigens (SPOA); Flagellar motor switch protein FliM; TIGRFAM: flagellar motor switch protein FliM.
  
  
 0.499
Deba_0862
COGs: COG3852 Signal transduction histidine kinase nitrogen specific; InterProIPR000014:IPR001610:IPR003661:IPR003594:IPR 001789:IPR005467:IPR000700:IPR011006:IPR009082:IPR004358:I PR013767:IPR000169; KEGG: sfu:Sfum_2401 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; histidine kinase A domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; PAS domain containing protein; PAC repeat-containing protein; histidine kinase A domain protein; response regulator receiver; SPTR: A0LKY0 Sensor p [...]
  
 
 0.491
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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