Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Deba_0363COGs: COG0482 tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase contains the PP-loop ATPase domain; KEGG: dol:Dole_2797 putative tRNA (5-methylaminomethyl-2-thiouridylate) -methyltransferase; SPTR: Q1K1V6 Thiamine biosynthesis protein; PFAM: Thiamine biosynthesis protein (ThiI). (329 aa)    
Predicted Functional Partners:
Deba_0364
Protein of unknown function DUF434; COGs: COG2454 conserved hypothetical protein; InterPro IPR007368; KEGG: scl:sce7378 hypothetical protein; PFAM: protein of unknown function DUF434; SPTR: A9EYI8 Uncharacterized conserved protein; PFAM: Protein of unknown function (DUF434).
       0.786
Deba_0362
Polyketide cyclase/dehydrase; InterPro IPR019587; KEGG: dol:Dole_0158 hypothetical protein; PFAM: Polyketide cyclase/dehydrase; SPTR: A8ZSQ5 Putative uncharacterized protein; PFAM: Polyketide cyclase / dehydrase and lipid transport.
       0.773
Deba_2144
COGs: COG0777 Acetyl-CoA carboxylase beta subunit; InterPro IPR000438:IPR011762:IPR011763:IPR000022; KEGG: gsu:GSU2370 acetyl-CoA carboxylase, carboxyl transferase, beta subunit; PFAM: carboxyl transferase; SPTR: Q74AI4 Acetyl-CoA carboxylase, carboxyl transferase, beta subunit; PFAM: Carboxyl transferase domain; TIGRFAM: acetyl-CoA carboxylase, carboxyl transferase, beta subunit.
  
  
 0.724
Deba_0365
COGs: COG0642 Signal transduction histidine kinase; InterProIPR013767:IPR003594:IPR001789:IPR011006:IPR 000014:IPR001610:IPR004358:IPR005467:IPR000700; KEGG: rpd:RPD_3277 ATP-binding region, ATPase-like; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; PAC repeat-containing protein; PAS domain containing protein; response regulator receiver; SPTR: Q134I8 Sensor protein; TIGRFAM: PAS sensor protein; PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-li [...]
     
 0.646
Deba_0366
COGs: COG0036 Pentose-5-phosphate-3-epimerase; InterPro IPR000056:IPR011060:IPR013785; KEGG: gyc:GYMC61_1959 ribulose-phosphate 3-epimerase; PFAM: ribulose-phosphate 3-epimerase; PRIAM: Ribulose-phosphate 3-epimerase; SPTR: C9RZQ3 Ribulose-phosphate 3-epimerase; TIGRFAM: ribulose-phosphate 3-epimerase; PFAM: Ribulose-phosphate 3 epimerase family; TIGRFAM: ribulose-phosphate 3-epimerase.
  
  
 0.632
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
  
  
 0.575
Deba_0352
Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
  
  
 0.556
Deba_2382
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
  
  
 0.518
rnpA
Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
  
  
 0.517
pheT
COGs: COG0072 Phenylalanyl-tRNA synthetase beta subunit; InterProIPR004532:IPR002547:IPR005121:IPR012340:IPR 020825:IPR005147:IPR016027:IPR009061:IPR005146; KEGG: sfu:Sfum_0429 phenylalanyl-tRNA synthetase, beta subunit; PFAM: B3/4 domain protein; t-RNA-binding domain protein; tRNA synthetase B5; ferredoxin-fold anticodon-binding; SPTR: A0LFC7 Phenylalanyl-tRNA synthetase beta subunit; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; PFAM: tRNA synthetase B5 domain; B3/4 domain; Ferredoxin-fold anticodon binding domain; Putative tRNA binding domain; TIGRFAM: phenylalanyl-tRNA synth [...]
  
  
 0.505
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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