STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Deba_0363COGs: COG0482 tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase contains the PP-loop ATPase domain; KEGG: dol:Dole_2797 putative tRNA (5-methylaminomethyl-2-thiouridylate) -methyltransferase; SPTR: Q1K1V6 Thiamine biosynthesis protein; PFAM: Thiamine biosynthesis protein (ThiI). (329 aa)    
Predicted Functional Partners:
mnmA
tRNA(5-methylaminomethyl-2-thiouridylate)-methyl transferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
     
  0.900
Deba_0364
Protein of unknown function DUF434; COGs: COG2454 conserved hypothetical protein; InterPro IPR007368; KEGG: scl:sce7378 hypothetical protein; PFAM: protein of unknown function DUF434; SPTR: A9EYI8 Uncharacterized conserved protein; PFAM: Protein of unknown function (DUF434).
       0.789
Deba_0362
Polyketide cyclase/dehydrase; InterPro IPR019587; KEGG: dol:Dole_0158 hypothetical protein; PFAM: Polyketide cyclase/dehydrase; SPTR: A8ZSQ5 Putative uncharacterized protein; PFAM: Polyketide cyclase / dehydrase and lipid transport.
       0.773
Deba_2144
COGs: COG0777 Acetyl-CoA carboxylase beta subunit; InterPro IPR000438:IPR011762:IPR011763:IPR000022; KEGG: gsu:GSU2370 acetyl-CoA carboxylase, carboxyl transferase, beta subunit; PFAM: carboxyl transferase; SPTR: Q74AI4 Acetyl-CoA carboxylase, carboxyl transferase, beta subunit; PFAM: Carboxyl transferase domain; TIGRFAM: acetyl-CoA carboxylase, carboxyl transferase, beta subunit.
  
    0.651
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
  
  
 0.649
Deba_0365
COGs: COG0642 Signal transduction histidine kinase; InterProIPR013767:IPR003594:IPR001789:IPR011006:IPR 000014:IPR001610:IPR004358:IPR005467:IPR000700; KEGG: rpd:RPD_3277 ATP-binding region, ATPase-like; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; PAC repeat-containing protein; PAS domain containing protein; response regulator receiver; SPTR: Q134I8 Sensor protein; TIGRFAM: PAS sensor protein; PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-li [...]
     
 0.649
Deba_2382
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
  
  
 0.603
Deba_0352
Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
  
  
 0.597
Deba_1143
Competence/damage-inducible protein CinA; COGs: COG1546 Uncharacterized protein (competence- and mitomycin-induced); InterPro IPR001453:IPR008136:IPR008135; KEGG: gme:Gmet_0196 competence/damage-inducible protein CinA; PFAM: CinA domain protein; molybdopterin binding domain; SPTR: C8QYB6 Competence/damage-inducible protein CinA; TIGRFAM: competence/damage-inducible protein CinA; PFAM: Probable molybdopterin binding domain; Competence-damaged protein; TIGRFAM: competence/damage-inducible protein CinA N-terminal domain; competence/damage-inducible protein CinA C-terminal domain; molybden [...]
  
    0.549
pheT
COGs: COG0072 Phenylalanyl-tRNA synthetase beta subunit; InterProIPR004532:IPR002547:IPR005121:IPR012340:IPR 020825:IPR005147:IPR016027:IPR009061:IPR005146; KEGG: sfu:Sfum_0429 phenylalanyl-tRNA synthetase, beta subunit; PFAM: B3/4 domain protein; t-RNA-binding domain protein; tRNA synthetase B5; ferredoxin-fold anticodon-binding; SPTR: A0LFC7 Phenylalanyl-tRNA synthetase beta subunit; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; PFAM: tRNA synthetase B5 domain; B3/4 domain; Ferredoxin-fold anticodon binding domain; Putative tRNA binding domain; TIGRFAM: phenylalanyl-tRNA synth [...]
  
  
 0.544
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.