STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Deba_0377Endonuclease/exonuclease/phosphatase; COGs: COG3568 Metal-dependent hydrolase; InterPro IPR005135; KEGG: sru:SRU_2696 endonuclease/exonuclease/phosphatase family protein, putative; PFAM: Endonuclease/exonuclease/phosphatase; SPTR: B4WQH8 Endonuclease/exonuclease/phosphatase family; PFAM: Endonuclease/Exonuclease/phosphatase family. (345 aa)    
Predicted Functional Partners:
mtaD
Amidohydrolase; Catalyzes the deamination of 5-methylthioadenosine and S- adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine. Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
       0.661
Deba_0376
Amidohydrolase; COGs: COG0402 Cytosine deaminase and related metal-dependent hydrolase; InterPro IPR006680:IPR011059; KEGG: sat:SYN_01991 chlorohydrolase/deaminase family protein; PFAM: amidohydrolase; SPTR: Q2LUH4 5-methylthioadenosine/S-adenosylhomocysteine deaminase 2; PFAM: Amidohydrolase family.
       0.661
Deba_0374
Inosine guanosine and xanthosine phosphorylase family; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
       0.612
Deba_0183
OmpA/MotB domain protein; COGs: COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)protein; InterPro IPR006665:IPR006690:IPR006664; KEGG: nha:Nham_0236 OmpA/MotB; PFAM: OmpA/MotB domain protein; SPTR: Q1QRL1 OmpA/MotB; PFAM: OmpA family.
   
  
 0.555
pal
Peptidoglycan-associated lipoprotein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
   
  
 0.555
Deba_1290
COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789:IPR013767:IPR003018:IPR013656:IPR 003661:IPR003594:IPR008207:IPR005467:IPR000014:IPR000700:I PR004358:IPR001610:IPR011006:IPR009082; KEGG: dvm:DvMF_1096 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS fold domain protein; GAF domain protein; PAS fold-4 domain protein; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS domain con [...]
 
  
 0.544
Deba_0207
Mannosyl-3-phosphoglycerate phosphatase family; COGs: COG3769 hydrolase (HAD superfamily); InterPro IPR013200:IPR006381:IPR006379; KEGG: rmr:Rmar_0501 mannosyl-3-phosphoglycerate phosphatase; PFAM: Haloacid dehalogenase domain protein hydrolase type 3; PRIAM: Mannosyl-3-phosphoglycerate phosphatase; SPTR: D0MEV3 Mannosyl-3-phosphoglycerate phosphatase; TIGRFAM: mannosyl-3-phosphoglycerate phosphatase family; HAD-superfamily hydrolase, subfamily IIB; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: mannosyl-3-phosphoglycerate phosphatase family; HAD-superfamily hydrolase, subfamily [...]
   
    0.493
Deba_0952
COGs: COG1286 membrane protein required for colicin V production; InterPro IPR003825; KEGG: dal:Dalk_3649 colicin V production protein; PFAM: Colicin V production protein; SPTR: B8FGV7 Colicin V production protein; PFAM: Colicin V production protein.
  
    0.490
Deba_0479
COGs: COG0077 Prephenate dehydratase; InterProIPR020822:IPR001086:IPR002912:IPR008242:IPR 002701:IPR018528; KEGG: pca:Pcar_1887 chorismate mutase-P and prephenate dehydratase; PFAM: prephenate dehydratase; Chorismate mutase, type II; amino acid-binding ACT domain protein; SPTR: Q1K0T9 Chorismate mutase; PFAM: Prephenate dehydratase; ACT domain; Chorismate mutase type II.
 
     0.474
Deba_1209
Polynucleotide adenylyltransferase region; COGs: COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; InterPro IPR001667:IPR003156:IPR000644:IPR002646; KEGG: sfu:Sfum_0679 polynucleotide adenylyltransferase region; PFAM: Polynucleotide adenylyltransferase region; CBS domain containing protein; phosphoesterase RecJ domain protein; phosphoesterase DHHA1; SMART: CBS domain containing protein; SPTR: A0LG26 Polynucleotide adenylyltransferase region; PFAM: DHH family; DHHA1 domain; CBS domain; Poly A polymerase head domain; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
       0.453
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.