STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Deba_0386COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR000873:IPR020845; KEGG: dal:Dalk_0599 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: B8FHL6 AMP-dependent synthetase and ligase; PFAM: AMP-binding enzyme. (550 aa)    
Predicted Functional Partners:
Deba_3227
COGs: COG0778 Nitroreductase; InterPro IPR000415:IPR001450:IPR017896:IPR017900; KEGG: dma:DMR_23050 nitroreductase family protein; PFAM: nitroreductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: C4XSV4 Nitroreductase family protein; PFAM: Nitroreductase family; 4Fe-4S binding domain.
  
 
 0.764
Deba_0387
Aryldialkylphosphatase; COGs: COG1735 metal-dependent hydrolase with the TIM-barrel fold; InterPro IPR001559:IPR017947; KEGG: dal:Dalk_0598 aryldialkylphosphatase; PFAM: aryldialkylphosphatase; SPTR: B8FHL5 Aryldialkylphosphatase; PFAM: Phosphotriesterase family.
       0.697
Deba_1863
COGs: COG1250 3-hydroxyacyl-CoA dehydrogenase; InterProIPR017441:IPR006176:IPR006108:IPR001753:IPR 016040:IPR008927:IPR013328; KEGG: chy:CHY_1609 3-hydroxyacyl-CoA dehydrogenase/enoyl-CoA hydratase/isomerase family protein; PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; 3-hydroxyacyl-CoA dehydrogenase domain protein; Enoyl-CoA hydratase/isomerase; SPTR: Q3ABP7 3-hydroxyacyl-CoA dehydrogenase/enoyl-CoA hydratase/isomerase family protein; PFAM: Enoyl-CoA hydratase/isomerase family; 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain.
 
 
 0.675
rplF
Ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.
    
 0.675
Deba_0032
COGs: COG1024 Enoyl-CoA hydratase/carnithine racemase; InterProIPR001753:IPR006176:IPR008927:IPR016040:IPR 013328; KEGG: hoh:Hoch_3456 3-hydroxyacyl-CoA dehydrogenase NAD-binding protein; PFAM: Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase NAD-binding; SPTR: D0LW26 3-hydroxyacyl-CoA dehydrogenase NAD-binding protein; PFAM: Enoyl-CoA hydratase/isomerase family.
  
 
 0.597
Deba_0086
COGs: COG1250 3-hydroxyacyl-CoA dehydrogenase; InterProIPR001753:IPR006176:IPR006108:IPR016040:IPR 008927:IPR018376:IPR013328; KEGG: 3-hydroxyacyl-CoA dehyrogenase, putative; PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain protein; SPTR: B9RKN5 3-hydroxyacyl-CoA dehyrogenase, putative; PFAM: Enoyl-CoA hydratase/isomerase family; 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Belongs to the enoyl-CoA hydratase/isomerase family.
  
 
 0.597
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
  
 
 0.587
Deba_1941
Peptidylprolyl isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
   
 
 0.552
rplB
Ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.
   
 
 0.550
Deba_0585
COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR000873; KEGG: dol:Dole_1973 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: A8ZT94 AMP-dependent synthetase and ligase; PFAM: AMP-binding enzyme.
 
 
0.544
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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