STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Deba_0445H(+)-transporting two-sector ATPase; COGs: COG0168 Trk-type K+ transport systems membrane components; InterPro IPR003445; KEGG: pca:Pcar_0086 TrkH family potassium uptake protein; PFAM: cation transporter; PRIAM: H(+)-transporting two-sector ATPase; SPTR: Q3A8E3 Potassium uptake protein, TrkH family; PFAM: Cation transport protein; TIGRFAM: potassium uptake protein, TrkH family. (454 aa)    
Predicted Functional Partners:
Deba_0444
TrkA-N domain protein; COGs: COG0569 K+ transport systems NAD-binding component; InterPro IPR003148:IPR006037:IPR016040; KEGG: dba:Dbac_0339 TrkA-N domain protein; PFAM: TrkA-N domain protein; TrkA-C domain protein; SPTR: C7LVC4 TrkA-N domain protein; PFAM: TrkA-N domain; TrkA-C domain.
 
 
 0.975
Deba_0023
Sodium/hydrogen exchanger; COGs: COG4651 Kef-type K+ transport system predicted NAD-binding component; InterPro IPR006153:IPR003148:IPR006037:IPR016040; KEGG: dvm:DvMF_1119 sodium/hydrogen exchanger; PFAM: sodium/hydrogen exchanger; TrkA-N domain protein; TrkA-C domain protein; SPTR: B8DKB1 Sodium/hydrogen exchanger; PFAM: TrkA-N domain; TrkA-C domain; Sodium/hydrogen exchanger family; TIGRFAM: potassium efflux system protein; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
  
 
 0.698
Deba_1084
TrkA-N domain protein; COGs: COG0569 K+ transport systems NAD-binding component; InterProIPR016040:IPR013099:IPR003148:IPR006037:IPR 000209; KEGG: glo:Glov_0875 TrkA-N domain protein; PFAM: TrkA-N domain protein; Ion transport 2 domain protein; TrkA-C domain protein; SPTR: B3E534 TrkA-N domain protein; PFAM: TrkA-N domain; Ion channel; TrkA-C domain.
 
 
 0.688
Deba_0610
TrkA-N domain protein; COGs: COG0569 K+ transport systems NAD-binding component; InterPro IPR003148:IPR006037:IPR016040:IPR006036; KEGG: dol:Dole_3218 potassium transporter peripheral membrane component; PFAM: TrkA-N domain protein; TrkA-C domain protein; SPTR: A9A0A2 TrkA-N domain protein; PFAM: TrkA-N domain; TrkA-C domain.
  
 
 0.654
Deba_1557
TrkA-N domain protein; COGs: COG0569 K+ transport systems NAD-binding component; InterPro IPR016040:IPR003148:IPR006037:IPR006036; KEGG: nth:Nther_0254 TrkA-N domain protein; PFAM: TrkA-N domain protein; TrkA-C domain protein; SPTR: B4WH73 TrkA-N domain family; PFAM: TrkA-N domain; TrkA-C domain.
  
 
 0.654
Deba_1377
KEGG: mvu:Metvu_0900 hypothetical protein; SPTR: C9RGQ6 Putative uncharacterized protein.
  
 
 0.619
Deba_1556
TrkA-N domain protein; COGs: COG0569 K+ transport systems NAD-binding component; InterPro IPR016040:IPR003148:IPR006036; KEGG: kol:Kole_0373 TrkA-N domain protein; PFAM: TrkA-N domain protein; SPTR: B4WH72 TrkA-N domain superfamily; PFAM: TrkA-N domain.
  
 
 0.619
surE
Stationary-phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
  
    0.542
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
     
 0.505
Deba_1290
COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789:IPR013767:IPR003018:IPR013656:IPR 003661:IPR003594:IPR008207:IPR005467:IPR000014:IPR000700:I PR004358:IPR001610:IPR011006:IPR009082; KEGG: dvm:DvMF_1096 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS fold domain protein; GAF domain protein; PAS fold-4 domain protein; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS domain con [...]
     
 0.472
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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