STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Deba_0509NUDIX hydrolase; InterPro IPR000086:IPR015797:IPR020084; KEGG: rmr:Rmar_0039 NUDIX hydrolase; PFAM: NUDIX hydrolase; SPTR: D0MK35 NUDIX hydrolase; PFAM: NUDIX domain; Belongs to the Nudix hydrolase family. (187 aa)    
Predicted Functional Partners:
prs
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
    
 0.912
Deba_0121
Phosphoglucomutase, alpha-D-glucose phosphate-specific; COGs: COG0033 Phosphoglucomutase; InterProIPR005844:IPR005845:IPR005846:IPR005843:IPR 016055:IPR016066:IPR005852; KEGG: gur:Gura_2654 phosphoglucomutase; PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase; SPTR: A5G4W1 Phosphoglucomutase, alpha-D-glucose phosphate-specific; TIGRFAM: phosphoglucomutase, alpha-D-glucose phosphate-specific; PFAM: [...]
   
 
 0.909
Deba_2695
Phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; COGs: COG1109 Phosphomannomutase; InterProIPR016066:IPR016055:IPR005844:IPR005845:IPR 005846:IPR005843:IPR005841; KEGG: sfu:Sfum_0481 phosphomannomutase; PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase; SPTR: A0LFH9 Phosphomannomutase; PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; Phosphoglucomutase/pho [...]
  
  0.905
ubiX
3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family.
   
 
  0.901
thiM
Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family.
     
  0.900
nnrD
Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...]
  
 0.895
birA
biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
 
    0.811
Deba_2577
Helicase domain protein; COGs: COG0553 Superfamily II DNA/RNA helicase SNF2 family; InterPro IPR014001:IPR001650:IPR000330:IPR014021; KEGG: sfu:Sfum_3846 helicase domain-containing protein; PFAM: helicase domain protein; SNF2-related protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: A0LQ13 Helicase domain protein; manually curated; PFAM: Helicase conserved C-terminal domain; SNF2 family N-terminal domain.
  
 0.785
Deba_0507
Diguanylate cyclase and serine/threonine protein kinase with TPR repeats; InterProIPR000160:IPR001440:IPR013105:IPR006597:IPR 011717:IPR019734:IPR011990:IPR013026; KEGG: drt:Dret_2188 diguanylate cyclase and serine/threonine protein kinase with TPR repeats; PFAM: Tetratricopeptide TPR_2 repeat protein; GGDEF domain containing protein; TPR repeat-containing protein; Sel1 domain protein repeat-containing protein; Tetratricopeptide TPR_4; SMART: GGDEF domain containing protein; Tetratricopeptide repeat; SPTR: C8X4X5 Diguanylate cyclase and serine/threonine protein kinase with TPR repeats; [...]
  
 
 0.740
selA
L-seryl-tRNA selenium transferase; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
       0.732
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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